Large platform vs smaller platform
Refills vs Novi: Track Record and Scale Compared (2026)
Refills or Novi? Side-by-side 2026 pricing, medication and service comparison, extended to six and twelve-month totals.
Published · Pricing as published in our provider dataset, synced · Editorial scores 7.7 and 7.0 out of 10
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Put Refills and Novi side by side and the marketing reads almost identically. The programs underneath do not.
One of these has been through the operational grind at scale and one is earlier in that curve: 50,124 reviews at Novi, 7,400 at Refills.
The comparison below starts from published pricing, converts it into annual cost, and then asks what the more expensive side is delivering for the difference. Undisclosed pricing is treated as a finding, not rounded into an estimate.
The short answer
- Lowest 12-month cost
- Refills — $1,188 against $1,596 at Novi, on each provider's own best published pricing.
- Most predictable bill
- Refills — Flat rate at every dose, so titration does not change what you are charged.
- Fastest route to a first shipment
- Refills — 3-minute approval quiz, then free, fast and discreet shipping on every order.
- Easiest to pay for
- Refills — Neither publishes financing; both expect the full amount monthly.
Refills vs Novi: the specification
The rows below are the ones that differ enough between these two to be worth your attention.
| Refills | Novi | |
|---|---|---|
| Advertised price | GLP-1 from $99/mo, about $5 a day | Semaglutide from $133/mo, tirzepatide from $166/mo |
| Rate after promotions | $99/mo | $133/mo |
| Pricing structure | Flat rate at every dose | Published rate per medication |
| Medication | Compounded semaglutide and GIP+GLP-1 dual agonist | Compounded semaglutide and compounded tirzepatide |
| Payment options | Card only, no financing published | Card only, no financing published |
| Membership fee | None | None |
| How fast you start | 3-minute approval quiz | Online intake |
| State coverage | Availability varies by state | Not published |
| Patient reviews | 7,400 | 50,124 |
| eRxDoctor score | 7.7/10 | 7.0/10 |
Refills vs Novi on total cost, not entry price
Comparing entry prices across these two would be actively misleading, because they escalate differently. The figures underneath convert both offers into what you will have spent by month six and month twelve.
| Refills | Novi | |
|---|---|---|
| First month | $99 | $133 |
| Months 2 onward | $99/mo | $133/mo |
| 6-month total | $594 | $798 |
| 12-month total | $1,188 | $1,596 |
| Best published plan | No multi-month discount published | No multi-month discount published |
Over a year that is a $408 difference, in Refills's favor. Whether it is the right call depends on whether Novi gives you $34 a month of something you will use.
Track record, and what review volume is worth
Novi has 50,124 reviews on record against 7,400 for Refills. Star ratings sit close together across this whole market, so the count is more informative than the score: it tells you how many times the operation has been tested.
Scale matters in this category for unglamorous reasons — pharmacy relationships that hold when demand spikes, support that answers on a Sunday, and a refund process that exists. Refills may run all of that well; there is simply less public evidence either way, and there is the standing caveat that clinicians come from partner networks and availability varies by state.
Weigh the smaller platform on what it publishes rather than what it lacks: $99 flat at every dosage, from LegitScript-certified pharmacies with third-party USP testing.
A closer look at Refills
Refills offers personalized compounded GLP-1 from $99/month (~$5/day) with flat pricing, the same price at every dosage, plus free discreet shipping, 24/7 health concierge support, and no membership or app fees. What it is really selling here is $99 flat at every dosage, from LegitScript-certified pharmacies with third-party USP testing.
Practically: 3-minute approval quiz, free, fast and discreet shipping on every order, and a pricing model that is flat rate at every dose.
Free 24/7 health concierge. The formulary covers compounded semaglutide and GIP+GLP-1 dual agonist.
Refills pros
- Free, fast, and discreet shipping on every order
- Free 24/7 Health Concierge support
- LegitScript-certified U.S. compounding pharmacies with third-party USP testing
- No insurance required, 3-minute approval quiz
Refills cons
- Clinicians come from partner telehealth networks (Beluga, Bask, Wasef Health)
- Compounded medication, not an FDA-approved branded product
- Availability varies by state
Against Novi specifically, the trade you are making: clinicians come from partner networks and availability varies by state.
Inside the Novi program
$200 OFF - GLP-1 for $133 Today In this pairing, its distinguishing feature is the narrowest gap here between semaglutide and tirzepatide pricing, at $133 and $166.
From signup to first shipment: online intake, then free 2-day shipping with every order. Billing follows a published rate per medication structure.
What continues after the first shipment: no long-term contract, cancel anytime. Formulary: compounded semaglutide and compounded tirzepatide.
Novi pros
- Competitive pricing: semaglutide from $133/month and tirzepatide from $166/month
- Largest patient base on this list, 50,000+ patients, signaling operational maturity
- Both compounded semaglutide and tirzepatide available
- Free 2-day shipping included with every order
Novi cons
- Compounded medication only, no branded Ozempic, Wegovy, or Zepbound
- Tirzepatide ($166) costs more than the semaglutide entry rate
- No published outcome or weight loss guarantee
The cost of choosing this over Refills: the $133 rate depends on a $200-off promotion and there is no outcome guarantee.
Picking between them
Choose Refills if:
- the feature you would actually use: $99 flat at every dosage, from LegitScript-certified pharmacies with third-party USP testing
- the twelve-month total is what you are optimizing ($1,188 against $1,596)
- you want the price you sign up at to survive titration
- the monthly rate is the constraint — $99/mo against $133/mo
Choose Novi if:
- you would rather use the platform with the longer public record (50,124 reviews)
- you would get real value from the narrowest gap here between semaglutide and tirzepatide pricing, at $133 and $166
- the level of clinical contact suits you: no long-term contract, cancel anytime
- you want to start on their timeline: online intake
Where each program concedes something
On price. Refills is the cheaper program at $99/mo against $133/mo. What Refills gives up for that is clinicians come from partner networks and availability varies by state; what Novi charges for is the narrowest gap here between semaglutide and tirzepatide pricing, at $133 and $166.
On clinical contact. The support models differ — free 24/7 health concierge against no long-term contract, cancel anytime — and that difference is felt in week two, not week one.
On medication. Refills covers compounded semaglutide and GIP+GLP-1 dual agonist; Novi covers compounded semaglutide and compounded tirzepatide. Neither locks you out of a molecule the other offers, so this is unlikely to be the deciding factor.
On access. Refills advertises 3-minute approval quiz and free, fast and discreet shipping on every order; Novi advertises online intake and free 2-day shipping with every order. Coverage differs too — availability varies by state against not published — which decides the question before price does if you are in a restricted state.
The medication, not the platform
Before either program's marketing claims, the underlying evidence — which belongs to the medication, not the platform.
The FDA publishes an ongoing record of semaglutide products marketed for diabetes and weight loss, and which of them it has actually approved, per FDA.
Dosing errors are the failure mode the FDA has flagged most often with unapproved GLP-1 products, particularly where a patient draws the dose themselves, per FDA.
Take the clinical questions to the prescribing clinician at whichever platform you choose; take the pricing questions to their support team before you pay.
Refills vs Novi: common questions
Which is cheaper to start, Refills or Novi?
Refills, at $99 against $133. Note that the cheapest first month and the cheapest year are often different providers here — check the 12-month row of the cost table before deciding on the entry price.
How fast can I start with Refills compared with Novi?
Refills advertises 3-minute approval quiz, with free, fast and discreet shipping on every order. Novi advertises online intake, with free 2-day shipping with every order. Both are subject to clinician review and to whether your state and health history clear, so treat the advertised timeline as a best case rather than a commitment.
Do Refills or Novi take insurance?
Both run on a direct-pay basis: you pay the platform and it does not bill your insurer. Neither publishes HSA/FSA acceptance, so budget the full amount as out-of-pocket spending.
Are Refills and Novi legitimate?
Both are licensed telehealth platforms that route a prescription through a clinician review before anything is dispensed; neither sells medication without one. Refills operates on flat rate at every dose with pricing published upfront, Novi on published rate per medication, published upfront. The meaningful due diligence is on the medication category and the terms, not on whether the platforms are real.
Is Refills or Novi better for a first GLP-1 prescription?
For a first prescription, weight support over price. Refills offers more contact (free 24/7 health concierge), which matters most in the first eight weeks when side effects and titration questions are at their peak. Once you know how you tolerate the medication, the cheaper program becomes the rational choice.
What happens if I stop taking the medication?
Both programs are month to month, which makes stopping easy and makes the consequence of stopping the thing to plan for: published extension data shows most of the lost weight returns within about a year. That is an argument for choosing on annual cost rather than entry price.
Do Refills and Novi prescribe the same medication?
Both dispense compounded GLP-1 preparations. Refills lists compounded semaglutide and GIP+GLP-1 dual agonist and Novi lists compounded semaglutide and compounded tirzepatide, so the molecules overlap even where the formulary does not match exactly.
The verdict
Refills is the cheaper year by $408, and for a straightforward course of treatment that settles it.
The case for Novi is the narrowest gap here between semaglutide and tirzepatide pricing, at $133 and $166. That is worth $34 a month to some patients and nothing at all to others — be honest about which you are.
Whichever way you go, the medication is the same class of drug and the clinical questions belong to a clinician. What you are choosing here is a billing model and a support structure.
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See every provider in context on the weight loss rankings, or browse the full comparison index.
Disclaimers and methodology
Medical content is informational only and does not replace professional diagnosis, treatment, or emergency care.
Some links are affiliate links and may generate commission at no extra cost to you.
Pricing reflects what each provider published as of the sync date above and changes frequently; confirm the current rate, and the rate at your maintenance dose, before you pay. Six- and twelve-month totals are calculated from those published rates and exclude anything a provider bills separately.
eRxDoctor is an independent publisher. It is not a medical provider, is not affiliated with or endorsed by Refills or Novi, and does not sell treatment. Read our ranking methodology.