Best NAD+ Therapy

Editorial score 9.9/10

• #1 Ranked
• Best Format Flexibility

He & She MD is a modern telehealth clinic offering NAD+ therapy in three delivery formats — a subcutaneous injection, a topical cream, and a nasal spray — all at a single flat price of $149/month on a 12-month supply. With no membership cost, no hidden fees, free expedited shipping, board-certified providers, and unlimited provider messaging, it's one of the most format-flexible NAD+ options available for people who want to choose how their therapy is delivered.

• Same $149/mo price across injection, cream, and nasal spray
• $149/mo pricing is based on a 12-month supply

Editorial score 9.8/10

• Best Overall
• 90-Day Money-Back Guarantee

Enhanced.com is our #1 NAD+ provider — a personalized, clinician-supervised NAD+Rx protocol restored to clinical levels and tailored to your goals. The current special offer is $139/month (regularly $232), with medication and ongoing care included, free 1–2 day shipping, and a 90-day money-back guarantee, no questions asked.

• NAD+Rx prescribed and monitored by board-certified providers
• 90-day money-back guarantee, no questions asked — free 1–2 day shipping

Editorial score 9.7/10

• Best Support

DirectMeds is one of the most established telehealth platforms for NAD+ therapy in the U.S., having served over 200,000 patients nationwide. Their NAD+ injection program saves you $100 on your first month, ships within 24–48 hours of approval, and pairs every patient with 24/7 nurse support, making it a strong choice for people who want a proven, supported experience without waiting weeks for an appointment.

• 500 mg plan renews at $199 per month
• Online consultation and shipping included

Editorial score 9.5/10

• Best Value
• Free Shipping

Remote Pharmacy offers 500mg and 1,000mg NAD+ injections from $99, with an online medical consultation, prescription, and free 1–2 day shipping included.

• Online medical consultation and prescription included
• Free shipping with estimated 1–2 day arrival

Editorial score 9.4/10

• Best Value

bmiMD offers NAD+ injection therapy starting at just $89/month, one of the lowest verified starting prices in the market. Every order includes free shipping from a licensed U.S. compounding pharmacy, and their no-risk refund policy means you get a full refund if your clinician does not approve you for treatment. For budget-conscious patients who don't want to compromise on quality, bmiMD is the strongest value option available.

• $89 pricing requires a 12-month plan
• Month-to-month treatment starts at $119

Editorial score 9.2/10

• Best Accessibility
• No Membership Fees

Wellmedr is a physician-supervised NAD+ injection platform offering one of the most accessible entry prices in the market at $99. With online medical evaluation, prescription management, no membership fees, and free home delivery, Wellmedr removes every barrier between you and quality NAD+ therapy.

• $99/mo starting — same price every dose, no membership
• 500mg and 1,000mg physician-supervised injections
• Free fast shipping · 4.7★ on Trustpilot (452 reviews)

Editorial score 9.0/10

• Best Overall
• 4.8 Stars

Embody is a telehealth platform specializing in NAD+ therapy, trusted by 180,000+ customers with a 4.8-star rating. Starting at $99/month with 500–1000mg injections available, free shipping, no membership fees, and no hidden costs, Embody makes pharmaceutical-grade NAD+ more accessible than any comparable provider.

• Online consultation and prescription process
• Recurring pricing applies after enrollment

Editorial score 8.7/10

• Best Value Guarantee

BettermeRx backs its NAD+ therapy with something almost no competitor offers: a 100% Success Guarantee. If you don't get results, you get your money back. Starting at $160/month with a limited-time $69 saving on the 1000mg injection plan, BettermeRx combines three delivery formats (injection 1000mg, injection 500mg, nasal spray 900mg) with real provider support and fast UPS/FedEx shipping.

• Online consultation and eligibility review included
• Multiple NAD+ treatment formats available

Editorial score 8.4/10

• Editor's Choice
• Lab-Tested Quality

ReadyRx is a fully online wellness platform that combines NAD+ therapy with personalized care planning, lab-tested medication quality, and an exclusive $20 off discount for new patients with code RXUMA2026. If you want a streamlined digital experience, no office visits, no phone tag, and care that covers multiple wellness goals beyond just NAD+, ReadyRx delivers a premium experience at a competitive price.

• Online medical evaluation included
• Pricing varies by dose and treatment format

Editorial score 7.8/10

• Best Personalized Care

RenuviaRX offers a board-certified physician-designed NAD+ protocol for $179 to start, with no insurance required and free shipping on every order. Where most NAD+ platforms focus purely on energy and cognition, RenuviaRX targets both cellular repair and anti-aging skin benefits alongside the traditional energy and mental clarity goals, making it a uniquely comprehensive protocol for patients who want to look younger and feel younger simultaneously.

• Online medical evaluation included
• Dose and treatment options depend on eligibility

Editorial score 7.8/10

• Best Personalized Care

Fridays is the only major NAD+ telehealth platform offering both injectable and nasal spray delivery formats, giving patients a genuine choice in how they receive treatment. Starting at $179/month, Fridays focuses on personalized care targeting energy, metabolism, and cognitive performance, and their clinical team designs a protocol specific to your goals rather than a one-size-fits-all approach.

• Online medical evaluation included
• Pricing may require quarterly prepayment

Editorial score 7.7/10

• Best Longevity Option

RNK Health is built specifically for performance-focused patients who want NAD+ therapy as part of a broader longevity and optimization strategy. Their protocols are designed around science-backed longevity research, and patients can track wellness metrics over time to measure actual results. The online intake takes about 15 minutes, making RNK one of the fastest platforms to get started for people who know what they want.

• Online medical consultation included
• At-home treatment available for eligible patients

Editorial score 7.7/10

• Best Budget Option

Sprout Health offers one of the most affordable ongoing NAD+ injection plans available, with monthly doctor check-ins included in the base price. While many providers charge extra for follow-up visits, Sprout builds physician oversight directly into every plan, making it the best option for patients who want long-term supervised care at a price that doesn't escalate month over month.

• Standard first-month pricing may be approximately $175
• Online medical consultation included

Editorial score 7.6/10

• Best Wellness Experience

Enhance MD provides a premium, medically supervised NAD+ injection experience with 1-on-1 physician consultations and fully customized dosing protocols. Unlike platforms that assign generic protocols, Enhance MD's physicians build your NAD+ plan around your specific biomarkers, lifestyle, and health goals, then provide ongoing medical support throughout your treatment to refine it over time.

• Online consultation and eligibility review included
• Multiple treatment approaches available

Editorial score 7.5/10

• Most Transparent Pricing

CareBareRx stands out in the NAD+ telehealth space by offering fully transparent, upfront pricing, you know exactly what you'll pay before you commit. No office visits, no surprise fees, and no hidden subscription charges. For patients who have been burned by confusing pricing from other platforms, CareBareRx's clean, straightforward model is a compelling reason to switch.

• Online medical consultation included
• Recurring monthly pricing applies

Editorial score 7.5/10

• Most Delivery Formats
• Established Platform

AgelessRx is a research-oriented longevity platform offering NAD+ as injections (500mg and 1,000mg), a nasal spray, and separate NAD patches. A $99 first-30-day promotion lowers the barrier to entry, but standard injection pricing is materially higher at $185/month for 500mg and $345/month for 1,000mg. Free discreet shipping and ongoing clinician support are included.

• One-time and subscription options available
• Online longevity consultation included

Editorial score 7.4/10

• Most Flexible
• Subscription or One-Time

Joi + Blokes is a premium longevity provider offering NAD+ as injections and a nasal spray, available by subscription or one-time purchase. The promotional injection price works out to about $100/month equivalent against a standard $172/month, but the injection plan is a 10-week supply billed as a monthly equivalent, so total-cost comparisons need care. It carries a strong 4.6/5 Trustpilot score across 1,350 reviews.

• NAD+ injections start at approximately $172 per month
• Pricing depends on the selected treatment format

Editorial score 7.3/10

• Lowest Intro Price
• Transparent Dose

Taurus sells a clinician-guided home-injection NAD+ program at $79 for the first month and $179 thereafter, with one of the most transparent dose disclosures in this comparison: a 200mg/mL concentration in a 5mL vial (1,000mg total). It is injection-only, ships from a licensed U.S. pharmacy, and is HSA/FSA eligible. Free shipping is not stated.

• Online consultation and prescription process
• Regular renewal pricing applies after the first month

Editorial score 7.2/10

• Injection & Nasal
• Best Value

System offers both injectable NAD+ from $89 and nasal NAD+ from $69 for the first month, with injection and nasal pricing shown separately.

• NAD+ nasal treatment starts at $69 for the first month
• Injection and nasal pricing shown separately

Editorial score 7.0/10

• Lower Cost on Longer Plans
• HSA/FSA Eligible

Tmates offers NAD+ treatment from $149 for one month, dropping to approximately $88 monthly on longer plans that require a plan commitment.

• Longer plans may reduce pricing to approximately $88 monthly
• Lowest price requires a longer plan commitment

Editorial score 7.0/10

• Needle-Free Nasal
• Best Value

Telos offers needle-free NAD+ nasal treatment from $49 for the first month, with the lowest pricing available on a 12-month plan.

• Lowest pricing may require a 12-month plan
• Nasal spray treatment — not injections

Editorial score 7.0/10

• Physician Consultation

RXSpan offers NAD+ treatment starting at approximately $249, with an online medical consultation included and recurring billing shown before checkout.

• Online medical consultation included
• Recurring billing shown before checkout

Editorial score 7.0/10

• Intro Pricing
• Best Value

Wellorithm offers NAD+ treatment from approximately $150 for the first month, rising to approximately $200 regular, with an online medical consultation included.

• Regular pricing may increase to approximately $200
• Online medical consultation included