Best Weight Loss Injections

Compare trusted weight loss options with transparent editorial analysis and side-by-side details.

Doctor-reviewed comparisons
Transparent pricing snapshots
Editorial testing framework

26 providers compared · Last updated August 1, 2026

We may receive compensation when you click partner links. Rankings are based on research methodology, not sponsorship.

Weight Loss providers, ranked

Shed

5.0(8,500)

Editorial score 9.9/10

Editor's Choice

Shed offers both name-brand and compounded GLP-1 weight loss medications with integrated coaching, a 2-minute approval assessment, and 10% off your first month.

Name-brand & compounded GLP-1 options
Continuous coaching. Not just a script.
2-minute approval assessment

Pros

Offers both FDA-approved name-brand GLP-1 and compounded options on one platform
Continuous coaching is integrated into treatment, not just a prescription
Fast 2-minute approval assessment

Cons

Standard pricing is not published, you receive a personalized quote after intake
Coaching-bundled model can cost more than bare-prescription platforms
Name-brand options carry significantly higher costs than compounded alternatives

Pricing

Get 10% Off your First Month

Best for

N/A

Visit Shed

Hers

4.9(6,200)

Editorial score 9.8/10

Hers offers FDA-approved Wegovy® (brand-name semaglutide) with a personalized care team and ongoing dose check-ins, no compounded medications.

FDA-approved Wegovy®, brand-name GLP-1 (no compounded medications)
Personalized care team with ongoing dose check-ins
No insurance required, cancel anytime

Pros

FDA-approved brand-name Wegovy®, not a compounded product
Personalized care team with ongoing dose check-ins
No insurance required

Cons

Higher starting price than most compounded competitors
No compounded/generic alternative offered

Pricing

Wegovy® pill from $149/mo · injectable from $199/mo

Best for

$149 (pill) · $199 (injectable pen)

Visit Hers

TrimRx

4.8(18,420)

Editorial score 9.7/10

TrimRx: 100k+ happy customers, 4.8 Excellent Rating. Compounded GLP-1 from $149/month and GLP-1+GIP from $249/month with Lifetime Price Protection, free 1–2 day shipping, 24/7 support, HSA/FSA eligible.

Starting at $149/month, GLP-1 & GLP-1+GIP in stock
Lifetime price lock — same price, every dose, no hidden fees
Free shipping, arrives in 1–2 days · 100k+ happy customers

Pros

100,000+ happy customers, one of the largest real-world patient bases in telehealth GLP-1
4.8 Excellent Rating from verified patient reviews
Both GLP-1 (semaglutide) starting at $149/month and GLP-1+GIP (tirzepatide) starting at $249/month available

Cons

Compounded medication only, no branded Ozempic, Wegovy, or Zepbound
GLP-1+GIP option at $249/month is higher than GLP-1-only entry price
Direct-pay model, insurance is not billed

Pricing

GLP-1 Plans Starting at $149/mo · Same price, every dose

Best for

Online GLP-1 weight loss care

Visit TrimRx

Yucca Health

4.8(36,958)

Editorial score 9.5/10

Yucca Health (TryYucca) review 2026: personalized compounded semaglutide from $146/month and tirzepatide from $258/month. Fast 24-hr approval, UPS 2-Day Air, Klarna/Affirm/Afterpay accepted.

Lifetime Price Lock with code YUCCA4LIFE — freeze $146/mo GLP-1 pricing for life
Compounded semaglutide from $146/month, or tirzepatide from $258/month
20,000+ active patients · 4.6 “Excellent” on TrustPilot (1,185+ reviews)
Board-certified providers licensed in all 50 states, U.S.-licensed pharmacies

Pros

Compounded semaglutide from $146/month, one of the lowest prices from a legitimate GLP-1 telehealth provider
Compounded tirzepatide from $258/month, dual GIP/GLP-1 mechanism for higher average weight loss
6-month semaglutide plan at $875 locks in the best per-month rate

Cons

No branded FDA-approved medications (Ozempic, Wegovy, Zepbound)
Does not accept health insurance
No weight loss warranty or outcome guarantee

Pricing

Semaglutide $146/mo · Tirzepatide $258/mo · 6-month plans available

Best for

Adults seeking affordable, personalized GLP-1 or GLP-1+GIP treatment with flexible payment options

Visit Yucca Health

Wellmedr

4.7(4,925)

Editorial score 9.4/10

GLP-1 Plans Starting at Just $89/Month

Lifetime locked-in pricing
No dose-based price increases
Same-day review + free overnight shipping

Pros

Lifetime locked-in pricing
No dose-based price increases

Pricing

Semaglutide from $89/mo, 1-Year Plan

Best for

$89 (yearly plan)

Visit Wellmedr

MedVi

4.6(12,896)

Editorial score 9.2/10

MedVi provides compounded semaglutide starting at $179/month with a simple online intake, no clinic visits, and 24/7 certified medical support for weight loss.

Simple Online Process, No Clinic Visits Needed
Clinically Dosed Compounded Semaglutide
24/7 Support From Certified Medical Professionals

Pros

Low promotional first month at $179 including fast, free shipping
Clinically dosed compounded semaglutide
24/7 support from certified medical professionals

Cons

Price increases sharply after the first month, $299 for a standalone month
Semaglutide only, no tirzepatide option
Compounded medication only, no branded Ozempic or Wegovy

Pricing

Winter Promo Applied! Only $179 + Fast, Free Shipping

Best for

$299

Visit MedVi

JoinFridays

4.5(6,985)

Editorial score 9.0/10

JoinFridays provides compounded GLP-1 weight loss options starting at $117/month, no long-term contracts, personalized clinician guidance, and active promo codes.

Compounded tirzepatide & semaglutide options
Personalized, clinician-guided care
No membership fees, cancel anytime

Pros

Lowest starting price in its tier at $117/month
Both compounded tirzepatide and semaglutide available on one platform
No membership fees, cancel anytime with no long-term contract

Cons

Compounded medication only, no branded Ozempic, Wegovy, or Zepbound
Promo code discounts are subject to change and may not always be available
Lowest tier ($117) reflects introductory or shortest-term pricing; monthly plan is $249

Pricing

Starting at $117/month

Best for

$249

Visit JoinFridays

altRx

4.4(14,820)

Editorial score 8.7/10

altRx is the most affordable GLP-1 program, limited offer: semaglutide $89/month and tirzepatide $149/month. 100% online medical visits, no membership, insurance or hidden fees, free and discreet 2-day delivery.

100% online medical visits
Buy now, pay later with Affirm, Klarna, Afterpay
No membership, insurance or hidden fees
No commitment, cancel anytime

Pros

Limited offer: semaglutide $89/mo and tirzepatide $149/mo, most affordable GLP-1 program on the market
100% online medical visits, no clinic appointments required
Buy now, pay later with Affirm, Klarna, Afterpay

Cons

Compounded medication, not FDA-approved branded product
Not available in all U.S. states

Pricing

Semaglutide from $89/mo · Tirzepatide from $149/mo

Best for

$89 (Semaglutide) · $149 (Tirzepatide)

Visit altRx

Enhance MD

4.2(10,482)

Editorial score 8.4/10

Enhance MD offers semaglutide from $49 and tirzepatide from $99 for your first month, with flat-rate pricing that stays the same at every dose, no fee escalation.

Semaglutide from $49, Tirzepatide from $99
Same price at every dose
10,000+ patients treated

Pros

Cheapest first month for both compounds, semaglutide from $49 and tirzepatide from $99
Flat-rate pricing: the same price at every dose, with no fee escalation during titration
Both semaglutide and tirzepatide available on one platform

Cons

The $49/$99 rates are first-month introductory prices; ongoing flat rate is higher
Compounded medication only, no branded Ozempic, Wegovy, or Zepbound
Ongoing flat-rate pricing not always prominently published before intake

Pricing

Starting at $49/first month (Semaglutide)

Best for

Flat rate, same price at every dose

Visit Enhance MD

Directmeds

3.9(3,400)

Editorial score 7.8/10

Directmeds is a licensed telehealth platform offering GLP-1 medications with a 50% first-month discount and nationwide shipping.

Licensed telehealth prescribing, GLP-1 medications
50% off first month for new patients
Nationwide shipping, no insurance required

Pros

50% off first month for new patients
Nationwide shipping, no insurance required
Licensed telehealth prescribing model

Cons

Standard (post-promo) pricing is not clearly disclosed upfront

Pricing

50% off first month, GLP-1 medications

Best for

Online GLP-1 weight loss care

Visit Directmeds

Measured

3.9(5,100)

Editorial score 7.8/10

Measured pairs compounded semaglutide and tirzepatide with same-day prescription decisions, unlimited provider messaging, and dietitian support.

Same-day prescription decisions, free 2-day shipping
Unlimited messaging, 24/7 Care Team, and dietitian support
4.8★ Trustpilot rating from 51,000+ users

Pros

Same-day prescription decisions for eligible patients
Unlimited messaging, 24/7 Care Team, and dietitian support included
4.8-star Trustpilot rating from 51,000+ users

Cons

Compounded medications are not FDA-approved finished products
Promotional pricing is time-limited

Pricing

Semaglutide $119/mo · Tirzepatide $199/mo (sale pricing)

Best for

$119 (Semaglutide) / $199 (Tirzepatide)

Visit Measured

Gala

3.9(2,870)

Editorial score 7.7/10

Gala GLP-1 is a direct-pay telehealth platform offering compounded semaglutide and tirzepatide with provider check-ins and home delivery.

Compounded semaglutide & tirzepatide, direct-pay, no insurance
Provider check-ins and dose monitoring included
Fully online, no in-office visits required

Pros

Direct-pay model, no insurance or prior authorizations needed
Provider check-ins and dose monitoring included
Fully online, no in-office visits required

Cons

Higher entry price than several compounded competitors
Lower long-term pricing requires a multi-month commitment

Pricing

From $249/mo · as low as $179/mo on longer plans

Best for

$249

Visit Gala

Refills

3.8(7,400)

Editorial score 7.7/10

Refills offers personalized compounded GLP-1 from $99/month (~$5/day) with flat pricing, the same price at every dosage, plus free discreet shipping, 24/7 health concierge support, and no membership or app fees.

Flat pricing, same price at every dosage
GLP-1 from $99/mo; GIP+GLP-1 dual agonist available
Free discreet shipping + 24/7 health concierge

Pros

Flat pricing, the same low price at every dosage, no titration upcharges
Personalized GLP-1 from $99/mo (~$5/day); GIP+GLP-1 dual agonist available
40% off new patient special offers

Cons

Compounded medication, not an FDA-approved branded product
Clinicians come from partner telehealth networks (Beluga, Bask, Wasef Health)
Availability varies by state

Pricing

GLP-1 from $99/mo (~$5/day)

Best for

From $99/mo, flat at every dose

Visit Refills

Embody

3.8(11,250)

Editorial score 7.6/10

Semaglutide $69/mo (was $299), Tirzepatide $119/mo

Semaglutide $69/month — was $299
Tirzepatide $119/month
Free shipping, delivered in 1–2 days

Pros

Lowest entry price on this list at $69/month for compounded semaglutide
Compounded tirzepatide available at $119/month
Free shipping with fast 1–2 day delivery after approval

Cons

Compounded medication only, no branded Ozempic, Wegovy, or Zepbound
Fewer premium features (no integrated coaching or advanced monitoring) than higher-priced platforms
Final pricing may vary based on dose and clinician recommendation

Pricing

$69/month semaglutide (was $299)

Best for

$69

Visit Embody

Wellorithm

3.8(3,240)

Editorial score 7.5/10

Take the 2-Minute Quiz to Check Your Eligibility

Compounded semaglutide & tirzepatide available
Licensed clinicians in all 50 states
Virtual consultations, medication shipped to home

Pros

Licensed clinicians in all 50 states, broader coverage than many smaller platforms
Both compounded semaglutide and tirzepatide available
Fully virtual consultations with medication shipped to your home

Cons

Pricing is not published, you only get a quote after completing the intake quiz
Compounded medication only, no branded Ozempic, Wegovy, or Zepbound
Smaller, less-established platform with limited public reviews

Pricing

Online GLP-1 Weight Loss Program

Best for

N/A

Visit Wellorithm

Ro.co

3.8(40,215)

Editorial score 7.5/10

Get Started Online for Just $39

Wegovy® Pill, FDA-approved oral GLP-1
Fastest GLP-1 at half the list price
No hidden fees

Pros

Only mainstream platform offering the FDA-approved Wegovy pill, oral GLP-1, no injections
Get started online for just $39
FDA-approved finished medication, not compounded

Cons

Branded and FDA-approved medications cost significantly more than compounded alternatives
Ongoing medication pricing varies and can be high depending on the plan
Less price-competitive than compounded-only platforms for budget-driven patients

Pricing

Get Started Online for Just $39

Best for

Online GLP-1 weight loss care

Visit Ro.co

Sprout Health

3.7(14,569)

Editorial score 7.4/10

Special Offer: Get $50 Off Your First Month

Fast, Safe & Hassle-Free: GLP-1 Medication
Lose 10–26% of Your Body Weight in 12 Months
Lightning-Quick Approval

Pros

$50 off the first month, bringing it to $199
Lightning-quick approval process
Clear outcome framing, 10–26% body weight loss over 12 months

Cons

Price rises to $249/month after the discounted first month
Higher ongoing cost than several competitors
Compounded medication only, no branded Ozempic or Wegovy

Pricing

Get $50 Off Your First Month

Best for

$249

Visit Sprout Health

Start Willow

3.7(6,385)

Editorial score 7.3/10

From $249 per Month

No Insurance Needed. No Membership Fees
Get Medication Like Ozempic® & Tirzepatide
Shipped to You in 3 Days or Less

Pros

No insurance needed and no membership fees
Medications comparable to Ozempic and tirzepatide
Delivery guaranteed in 3 days or less

Cons

Price rises from $249 first month to $299/month ongoing
Ongoing $299/month is among the higher rates on this list
Compounded medication only, no branded Ozempic or Wegovy

Pricing

From $249 per Month

Best for

$299

Visit Start Willow

IVIM Health

3.6(36,958)

Editorial score 7.2/10

Limited Offer: Free Month Membership – Use Code GIFT75

No Obligation Free Consult ($75 value)
4.9 Stars on Google and Trustpilot
Lose Weight 40% Faster with GLP-1 ID by Ivim

Pros

4.9-star rating on both Google and Trustpilot, rare dual third-party verification
No-obligation free consultation ($75 value) for new patients
Free month membership with code GIFT75

Cons

The 40% faster claim is a proprietary protocol claim, not an independent clinical finding
Price rises from $99 first month to $174/month ongoing
Compounded medication only, no branded Ozempic or Wegovy

Pricing

Free Month Membership with Code GIFT75

Best for

$174

Visit IVIM Health

Elevate Health

3.5(29,722)

Editorial score 7.0/10

Elevate Health offers compounded semaglutide from $133/month and tirzepatide from $197/month, with lab tests included and a fully remote intake.

Save $300 with code BFCM300
Tirzepatide from $197/month
Free lab tests included

Pros

Semaglutide from $133/mo and tirzepatide from $197/mo
Free lab tests included, unlike programs that bill them separately
Fully remote process, no in-person visits required

Cons

Compounded medications only, not FDA-approved brand-name products
Cash-pay model; insurance is not billed
The $300 discount requires promo code BFCM300, verify it is still active

Pricing

Save $300 on Any Order (Use Code BFCM300)

Best for

N/A

Visit Elevate Health

TMates

3.5(21,970)

Editorial score 7.0/10

$199/month, every dose, no step-up fees

Meds formulated in the USA
Clinically Dosed Compounded Semaglutide
24/7 U.S. doctor access, all 50 states

Pros

Flat $199/month at every dose, no step-up fees as dosage escalates
24/7 access to U.S.-based doctors, not just messaging support
Licensed coverage in all 50 states

Cons

$199/month is higher than the cheapest compounded options
Compounded semaglutide only, limited public detail on tirzepatide availability
No branded Ozempic, Wegovy, or Zepbound

Pricing

$199/month, every dose, no step-up fees

Best for

Online GLP-1 weight loss care

Visit TMates

Mochi Health

3.5(36,124)

Editorial score 7.0/10

50% Off Your 1st Month with Code BESTWLHALFOFF

Book a Live Video Visit With a Doctor in 5 Minutes
Reliable GLP-1 Prescription Access, All 50 States
24/7 Support + Ongoing Appointments Anytime, Anywhere

Pros

Live video visits with a doctor, bookable in about 5 minutes (most competitors do async text review)
50% off your first month with code BESTWLHALFOFF
Reliable GLP-1 prescription access in all 50 states

Cons

Pricing is membership plus medication, so total monthly cost varies by plan and medication
Ongoing pricing is less transparent than flat-rate competitors
Compounded medication focus, branded options not the primary offering

Pricing

50% Off Your 1st Month

Best for

Membership + meds from $99/month

Visit Mochi Health

Novi

3.5(50,124)

Editorial score 7.0/10

$200 OFF - GLP-1 for $133 Today

Semaglutide from $133/mo, Tirzepatide from $166/mo
50,000+ patients. Proven results.
Free 2-day shipping. No insurance needed.

Pros

Largest patient base on this list, 50,000+ patients, signaling operational maturity
Competitive pricing: semaglutide from $133/month and tirzepatide from $166/month
Free 2-day shipping included with every order

Cons

Compounded medication only, no branded Ozempic, Wegovy, or Zepbound
Tirzepatide ($166) costs more than the semaglutide entry rate
No published outcome or weight loss guarantee

Pricing

Starting at $133/month

Best for

$133 (Semaglutide) / $166 (Tirzepatide)

Visit Novi

LIV Body

3.5(125,000)

Editorial score 7.0/10

LIV Body is a flat-rate compounded semaglutide program at $249/month with 24/7 unlimited messaging, a weight loss guarantee, and 125,000+ members.

Flat-rate pricing, same price every dose
No hidden fees or insurance needed
24/7 physician & nurse support

Pros

Flat-rate pricing, the same price at every dose with no hidden fees
24/7 unlimited messaging with physicians and nurses
Weight loss guarantee backing the program

Cons

Uses compounded GLP-1 medications, not brand-name FDA-approved drugs
At $249/mo it is well above the cheapest compounded competitors

Pricing

Starting at $249/month

Best for

$249 (flat rate at all doses)

Visit LIV Body

Maximus

3.5(2,896)

Editorial score 7.0/10

$132.99 per Month

Convenient telemedicine access
Approved by licensed doctors
Using trusted US pharmacies

Pros

Low flat rate at $132.99/month
Convenient telemedicine access with no clinic visits
Prescriptions approved by licensed doctors

Cons

Smallest patient base on this list, limited public reviews and track record
Compounded medication only, no branded Ozempic, Wegovy, or Zepbound
Limited published detail on tirzepatide availability and program features

Pricing

Start with $133 Per Month

Best for

Online GLP-1 weight loss care

Visit Maximus

He & She MD

3.5(4,180)

Editorial score 7.0/10

Best Bundled Coaching

He & She MD bundles compounded GLP-1 medication with a coaching app that carries 1:1 clinician messaging, GLP-1-specific guidance and progress tracking. Semaglutide injections start at $139/month, oral semaglutide and tirzepatide at $199/month, each a six-month introductory rate. Free expedited shipping, no membership fee, no insurance required.

1:1 clinician messaging, GLP-1 coaching & tracking included in the app
Semaglutide injection, oral semaglutide, or tirzepatide injection
Free expedited shipping, no membership fee, no insurance needed

Pros

Coaching app, 1:1 clinician messaging and progress tracking included at no extra cost
Three formats: semaglutide injection, oral semaglutide, tirzepatide injection
$139/mo intro price is competitive for a program with this much bundled support

Cons

Headline prices are 6-month intro rates that renew 30-45% higher
Pricing is structured as six-month terms, not true month-to-month
Compounded GLP-1s are not reviewed by the FDA for safety, efficacy or quality

Pricing

Semaglutide from $139/mo · Tirzepatide from $199/mo

Best for

$139 semaglutide · $199 oral · $199 tirzepatide (6-mo intro)

Visit He & She MD

How to choose

Focus on provider quality, treatment transparency, and follow-up support when evaluating weight loss options.

How it works

Complete an online intake, review your options with a licensed professional when applicable, and begin a plan tailored to your goals.

What you get

Convenient online access
Personalized treatment planning
Flexible service options

Weight Loss questions, answered

How do Weight Loss Injections like Ozempic® Work?

Weight loss injections like Ozempic® work by utilizing a medication called semaglutide, which is a GLP-1 receptor agonist. This type of medication helps regulate blood sugar levels and can also reduce appetite by affecting areas of the brain that control hunger. By reducing cravings and slowing down the rate at which food leaves the stomach, these injections help you eat less and feel fuller for longer, leading to weight loss over time. When combined with a healthy diet and regular exercise, Ozempic® and similar treatments can support significant weight loss.

Who is Eligible for Weight Loss Injections?

Eligibility for weight loss injections typically depends on your BMI and overall health. Generally, these medications are prescribed for adults with a BMI of 30 or higher, or a BMI of 27 or higher with weight-related health conditions such as type 2 diabetes or high blood pressure. A healthcare provider will evaluate your medical history, current health status, and weight loss goals to determine if weight loss injections are appropriate for you.

Are there any Side Effects?

Yes, like any medication, weight loss injections can have side effects. Common side effects include nausea, headaches, mild digestive issues, redness or swelling at the injection site, and occasional dizziness. Most side effects are mild and tend to improve as your body adjusts to the medication. However, it's important to discuss potential risks with your healthcare provider and report any severe or persistent symptoms immediately.

How Quickly can I Expect Results?

Results vary from person to person, but many people begin to see weight loss within the first few weeks of treatment. Most individuals experience gradual, sustainable weight loss over several months. Clinical studies show that significant weight loss typically occurs within 3-6 months when combined with a healthy diet and regular physical activity. Consistency with treatment and lifestyle changes is key to achieving the best results.

Are Weight Loss Injections Covered by Insurance?

Insurance coverage for weight loss injections varies depending on your provider and plan. Some insurance companies cover medications like Ozempic®, Wegovy, or Saxenda when prescribed for medical conditions such as type 2 diabetes or obesity with related health issues. However, coverage for weight loss alone may not be guaranteed. It's best to check with your insurance provider directly to understand your coverage options and any out-of-pocket costs.

What are the Most Popular Weight Loss Injection Brands?

The most popular weight loss injection brands include Ozempic® (semaglutide), Wegovy (semaglutide), Saxenda (liraglutide), Mounjaro (tirzepatide), and Zepbound (tirzepatide). Each of these medications works by targeting appetite control and metabolism, though they may differ in dosing frequency, effectiveness, and side effect profiles. Your healthcare provider can help determine which option is best suited to your individual needs and health goals.

Disclaimers

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