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Coaching-supported vs medication-only

MedVi vs He & She MD: Coaching Included, or Just a Script? (2026)

MedVi $299/mo vs He & She MD $191/mo. 2026 comparison of pricing, medication and support, with 12-month totals rather than first-month offers.

Published · Pricing as published in our provider dataset, synced · Editorial scores 9.2 and 7.0 out of 10

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Comparing MedVi with He & She MD means comparing two business models more than two medications. The molecules overlap; the terms do not.

The real difference is what happens between refills. He & She MD puts coaching app with 1:1 clinician messaging and progress tracking, no extra charge inside the monthly price; MedVi leaves that to you and charges accordingly.

Rather than restate two feature lists, this compares the two on cost over time, medication access, price stability and the support each one includes. Where a figure is not published, that is stated rather than estimated.

The short answer

Lowest 12-month cost
He & She MD$1,980 against $2,592 at MedVi, on each provider's own best published pricing.
Most support for the money
He & She MDCoaching app with 1:1 clinician messaging and progress tracking, no extra charge.
Tirzepatide access
He & She MDTirzepatide at $199/mo; the other side publishes semaglutide only.
Longest public track record
MedVi12,896 patient reviews against 4,180.

Side-by-side comparison

Two programs, side by side, on their own published terms — with the rows that differ doing the work.

 MedViHe & She MD
Advertised price$179 promotional first monthSemaglutide from $139/mo, oral semaglutide and tirzepatide from $199/mo
Rate after promotions$299/mo$191/mo
Pricing structurePromotional first month, then standard rateIntroductory term, then renewal at a higher rate
MedicationCompounded semaglutideCompounded semaglutide injection, oral semaglutide and compounded tirzepatide injection
Support modelNo coaching program statedCoaching built into the plan
How fast you startSimple online process, no clinic visits2-3 minute intake with no payment required to check eligibility
Membership feeNoneNone
State coverageNot publishedNot published
TirzepatideNot published$199/mo
Patient reviews12,8964,180
eRxDoctor score9.2/107.0/10

What MedVi and He & She MD actually cost over a year

A first-month price is a customer-acquisition number. Here is what each one costs across a realistic course of treatment, on published pricing.

 MedViHe & She MD
First month$179$139
Months 2 onward$299/mo$191/mo
6-month total$1,674$834
12-month total$3,468$1,980
Best published plan3-month plan at $649 — $2,592/yrNo multi-month discount published

Over a year that is a $612 difference, in He & She MD's favor. Whether it is the right call depends on whether MedVi gives you $51 a month of something you will use.

Price escalation to plan for: MedVi moves from $179 to $299, a 67% increase and He & She MD moves from $139 to $191, a 37% increase. Set a calendar reminder for the month it changes.

Coaching, or just the prescription

He & She MD includes coaching app with 1:1 clinician messaging and progress tracking, no extra charge. That is a real cost to deliver, and it is priced into the monthly rate whether or not you open the app.

MedVi is built the other way: 24/7 support from certified medical professionals. The medication does the pharmacological work, and everything around it is yours to organize.

Coaching is the line item people cancel first and miss most. Be honest about which patient you are before optimizing it away.

MedVi: what you are buying

MedVi provides compounded semaglutide starting at $179/month with a simple online intake, no clinic visits, and 24/7 certified medical support for weight loss.

The process is simple online process, no clinic visits, then fast, free shipping. On money, expect promotional first month, then standard rate — published upfront.

What continues after the first shipment: 24/7 support from certified medical professionals. Formulary: compounded semaglutide.

MedVi pros

  • Simple online process with no clinic visits required
  • 24/7 support from certified medical professionals
  • Clinically dosed compounded semaglutide
  • Low promotional first month at $179 including fast, free shipping

MedVi cons

  • Compounded medication only, no branded Ozempic or Wegovy
  • No published outcome or weight loss guarantee
  • Price increases sharply after the first month, $299 for a standalone month

The cost of choosing this over He & She MD: the price roughly doubles to $299 once the promotional month ends.

Inside the He & She MD program

The pitch is three medication formats and a coaching app included, under a named board-certified obesity-medicine CMO. He & She MD bundles compounded GLP-1 medication with a coaching app that carries 1:1 clinician messaging, GLP-1-specific guidance and progress tracking. Semaglutide injections start at $139/month, oral semaglutide and tirzepatide at $199/month, each a six-month introductory rate. Free expedited shipping, no membership fee, no insurance required.

You start with 2-3 minute intake with no payment required to check eligibility; medication arrives via free expedited shipping with no upcharges. The price behaves as introductory term, then renewal at a higher rate.

On the clinical side, coaching app with 1:1 clinician messaging and progress tracking, no extra charge, prescribing compounded semaglutide injection, oral semaglutide and compounded tirzepatide injection.

He & She MD pros

  • $139/mo intro price is competitive for a program with this much bundled support
  • Named, dual board-certified obesity-medicine Chief Medical Officer
  • Coaching app, 1:1 clinician messaging and progress tracking included at no extra cost
  • Three formats: semaglutide injection, oral semaglutide, tirzepatide injection

He & She MD cons

  • The 15-25 lbs in 12 weeks figure is self-reported retrospective data, not trial data
  • Compounded GLP-1s are not reviewed by the FDA for safety, efficacy or quality
  • Pricing is structured as six-month terms, not true month-to-month

The reservation worth holding, particularly next to MedVi: the headline rates are six-month terms that renew 30-45% higher.

Who each program is actually built for

Choose MedVi if:

  • delivery works the way you want it to: fast, free shipping
  • you are willing to commit for a term in exchange for a lower effective rate (3-month plan at $649)
  • what it leads on is worth paying for in your case: a genuinely low promotional entry point with 24/7 clinical support behind it
  • the level of clinical contact suits you: 24/7 support from certified medical professionals

Choose He & She MD if:

  • you would get real value from three medication formats and a coaching app included, under a named board-certified obesity-medicine CMO
  • the level of clinical contact suits you: coaching app with 1:1 clinician messaging and progress tracking, no extra charge
  • you want to start on their timeline: 2-3 minute intake with no payment required to check eligibility
  • delivery works the way you want it to: free expedited shipping with no upcharges

The compromises on both sides

On price. He & She MD is the cheaper program at $191/mo against $299/mo. What He & She MD gives up for that is the headline rates are six-month terms that renew 30-45% higher; what MedVi charges for is a genuinely low promotional entry point with 24/7 clinical support behind it.

On commitment. MedVi rewards a longer commitment (3-month plan at $649), which lowers the effective rate but ties up money before you know how you respond to the medication. Neither publishes financing options, so plan for the full amount each month.

On medication. MedVi covers compounded semaglutide; He & She MD covers compounded semaglutide injection, oral semaglutide and compounded tirzepatide injection. Only He & She MD publishes a tirzepatide route, which matters if semaglutide underdelivers.

On clinical contact. MedVi provides 24/7 support from certified medical professionals. He & She MD provides coaching app with 1:1 clinician messaging and progress tracking, no extra charge. Both are asynchronous-first services and neither replaces a physician who can examine you.

The medication, not the platform

The efficacy data people cite when comparing these platforms is not platform data. It comes from trials of the underlying medication, and it applies to both.

NIDDK frames medication as one component of obesity treatment rather than a replacement for the rest of it, per NIH, NIDDK.

The STEP 1 extension found participants regained roughly two-thirds of the weight they had lost within a year of stopping semaglutide, per Diabetes, Obesity and Metabolism.

None of that settles which of these two to use. It does mean the drug is doing the work, and you are choosing who supplies it and on what terms.

MedVi vs He & She MD: common questions

Which is cheaper to start, MedVi or He & She MD?

He & She MD, at $139 against $179. Note that the cheapest first month and the cheapest year are often different providers here — check the 12-month row of the cost table before deciding on the entry price.

How fast can I start with MedVi compared with He & She MD?

MedVi advertises simple online process, no clinic visits, with fast, free shipping. He & She MD advertises 2-3 minute intake with no payment required to check eligibility, with free expedited shipping with no upcharges. Both are subject to clinician review and to whether your state and health history clear, so treat the advertised timeline as a best case rather than a commitment.

Are MedVi and He & She MD legitimate?

Both are licensed telehealth platforms that route a prescription through a clinician review before anything is dispensed; neither sells medication without one. MedVi operates on promotional first month, then standard rate with pricing published upfront, He & She MD on introductory term, then renewal at a higher rate, published upfront. The meaningful due diligence is on the medication category and the terms, not on whether the platforms are real.

What happens if I stop taking the medication?

Both programs are month to month, which makes stopping easy and makes the consequence of stopping the thing to plan for: published extension data shows most of the lost weight returns within about a year. That is an argument for choosing on annual cost rather than entry price.

Is MedVi or He & She MD better for a first GLP-1 prescription?

First-timers usually get more from clinical access than from a lower rate, because the first two months are where most people stop. On that basis He & She MD has the stronger case; after month three, cost should take over.

Can I switch from MedVi to He & She MD later?

You can, and people do — usually when an introductory price expires. Budget for a repeat intake and a short overlap in supply, and confirm what happens to any unused portion of a multi-month plan before you cancel it.

The verdict

On the numbers, He & She MD wins the year: $1,980 against $2,592. That is the default answer, and it is the right one for anyone who mainly needs a reliable prescription and a shipment that arrives.

The case for MedVi is a genuinely low promotional entry point with 24/7 clinical support behind it. That is worth $51 a month to some patients and nothing at all to others — be honest about which you are.

Get the maintenance-dose price in writing from whichever one you pick. That single question prevents most of the regret in this category.

Keep comparing

See every provider in context on the weight loss rankings, or browse the full comparison index.

Disclaimers and methodology

Medical content is informational only and does not replace professional diagnosis, treatment, or emergency care.

Some links are affiliate links and may generate commission at no extra cost to you.

Pricing reflects what each provider published as of the sync date above and changes frequently; confirm the current rate, and the rate at your maintenance dose, before you pay. Six- and twelve-month totals are calculated from those published rates and exclude anything a provider bills separately.

eRxDoctor is an independent publisher. It is not a medical provider, is not affiliated with or endorsed by MedVi or He & She MD, and does not sell treatment. Read our ranking methodology.