Brand-name vs compounded
Hers vs Enhance MD: Brand-Name or Compounded? (2026)
Compare Hers and Enhance MD on real cost over 12 months, medication type, price stability and support. Independent 2026 analysis, no first-month gimmicks.
Published · Pricing as published in our provider dataset, synced · Editorial scores 9.8 and 8.4 out of 10
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Both Hers and Enhance MD will get a GLP-1 prescription to your door without an in-person visit. The question is what the year after that first shipment looks like.
Choosing between them is really choosing between an approved finished drug and a compounded preparation. Hers sits on one side of that line and Enhance MD on the other, and no amount of feature comparison makes the distinction go away.
What follows is a like-for-like read of both programs: entry pricing, maintenance pricing, formulary, support model and the terms attached to each. Every figure traces back to the provider's own published material, and the missing ones stay missing.
The short answer
- Lowest ongoing rate
- Enhance MD — $49/mo against $149/mo, though only one of the two publishes enough to total a full year.
- FDA-approved medication
- Hers — FDA-approved Wegovy pill (oral semaglutide) and Wegovy injectable pen — a finished product the FDA has reviewed, rather than a compounded preparation.
- Tirzepatide access
- Enhance MD — Tirzepatide at $99/mo; the other side publishes semaglutide only.
- Most support included
- Hers — Personalized care team with ongoing dose check-ins.
Hers vs Enhance MD at a glance
Every figure below is the provider's own published number. The blank spaces are theirs, not ours.
| Hers | Enhance MD | |
|---|---|---|
| Advertised price | Wegovy pill from $149/mo, injectable from $199/mo | Semaglutide from $49, tirzepatide from $99, first month |
| Rate after promotions | $149/mo | $49/mo |
| Pricing structure | Published rate per medication | Flat rate at every dose |
| Medication | FDA-approved Wegovy pill (oral semaglutide) and Wegovy injectable pen | Compounded semaglutide and compounded tirzepatide |
| State coverage | Not published | Not published |
| How fast you start | Online intake with clinician review | Online intake |
| Membership fee | None | Not stated |
| Payment options | Card only, no financing published | Card only, no financing published |
| Patient reviews | 6,200 | 10,482 |
| eRxDoctor score | 9.8/10 | 8.4/10 |
What Hers and Enhance MD actually cost over a year
Trial data runs to 68 and 72 weeks; the pricing people compare runs to 30 days. So the table works in the timeframe treatment actually happens in.
| Hers | Enhance MD | |
|---|---|---|
| First month | $149 | $49 |
| Months 2 onward | $149/mo | Not published |
| 6-month total | $894 | Not computable |
| 12-month total | $1,788 | Not computable |
| Best published plan | No multi-month discount published | No multi-month discount published |
A like-for-like annual total is not available for Enhance MD: the ongoing flat rate is higher than the $49 introductory month and is not prominently published before intake. Treat any comparison that quotes one as an estimate someone else has made for you.
What is actually in the vial
Hers dispenses FDA-approved Wegovy pill (oral semaglutide) and Wegovy injectable pen: an approved finished drug, meaning the agency has reviewed both the evidence behind it and the facility that makes it.
Enhance MD supplies compounded semaglutide and compounded tirzepatide — compounded medication prepared by a pharmacy rather than manufactured under an approved application. That is what makes $49/mo possible in the first place, and it is also why the oversight is not the same.
The honest framing is a trade, not a ranking. Compounded access is what has put GLP-1 treatment within reach of people whose insurance will not cover it; approved product is what removes a category of uncertainty about what is in the vial. Both of those are real.
How Hers works
Hers offers FDA-approved Wegovy® (brand-name semaglutide) with a personalized care team and ongoing dose check-ins, no compounded medications.
From signup to first shipment: online intake with clinician review, then home delivery, no insurance required. Billing follows a published rate per medication structure.
Support: personalized care team with ongoing dose check-ins. The medications on offer are FDA-approved Wegovy pill (oral semaglutide) and Wegovy injectable pen.
Hers pros
- Personalized care team with ongoing dose check-ins
- FDA-approved brand-name Wegovy®, not a compounded product
- No insurance required
Hers cons
- Higher starting price than most compounded competitors
- No compounded/generic alternative offered
The cost of choosing this over Enhance MD: there is no compounded tier to fall back on if the brand-name price stops working for you.
Inside the Enhance MD program
Enhance MD positions itself on the lowest first month anywhere on this list, on both compounds. Enhance MD offers semaglutide from $49 and tirzepatide from $99 for your first month, with flat-rate pricing that stays the same at every dose, no fee escalation.
You start with online intake; medication arrives via home delivery. The price behaves as flat rate at every dose.
Ongoing care is 10,000+ patients treated, and the medication list runs to compounded semaglutide and compounded tirzepatide.
Enhance MD pros
- No hidden fees at higher doses
- Cheapest first month for both compounds, semaglutide from $49 and tirzepatide from $99
- Flat-rate pricing: the same price at every dose, with no fee escalation during titration
- Both semaglutide and tirzepatide available on one platform
Enhance MD cons
- Compounded medication only, no branded Ozempic, Wegovy, or Zepbound
- The $49/$99 rates are first-month introductory prices; ongoing flat rate is higher
- Ongoing flat-rate pricing not always prominently published before intake
Against Hers specifically, the trade you are making: what you pay in month two is the number that is missing.
Which one fits which patient
Choose Hers if:
- delivery works the way you want it to: home delivery, no insurance required
- you want to start on their timeline: online intake with clinician review
- the level of clinical contact suits you: personalized care team with ongoing dose check-ins
- what it leads on is worth paying for in your case: brand-name Wegovy at a price that usually buys compounded medication elsewhere
Choose Enhance MD if:
- you would get real value from the lowest first month anywhere on this list, on both compounds
- you want tirzepatide available without changing provider later
- you want the price you sign up at to survive titration
- the monthly rate is the constraint — $49/mo against $149/mo
The trade-offs, stated plainly
On price. Enhance MD is the cheaper program at $49/mo against $149/mo. What Enhance MD gives up for that is what you pay in month two is the number that is missing; what Hers charges for is brand-name Wegovy at a price that usually buys compounded medication elsewhere.
On commitment. Neither publishes a multi-month discount, so both are month-to-month decisions and neither asks you to prepay for a response you have not had yet. Neither publishes financing options, so plan for the full amount each month.
On predictability. The pricing structures differ (published rate per medication versus flat rate at every dose), and structure, not headline rate, determines the twelve-month bill.
On access. Hers advertises online intake with clinician review and home delivery, no insurance required; Enhance MD advertises online intake and home delivery. Neither publishes its state coverage, so confirm you are eligible before paying for anything.
What the evidence actually says
Weight loss percentages quoted in telehealth marketing come from trials neither Hers nor Enhance MD ran. Here is the source material, and what regulators say alongside it.
NIDDK frames medication as one component of obesity treatment rather than a replacement for the rest of it, per NIH, NIDDK.
The FDA approved tirzepatide for chronic weight management in November 2023, two years after semaglutide, per FDA.
Use it as the floor for the conversation with whichever prescriber you end up with, rather than as a reason to pick one platform over the other.
Hers vs Enhance MD: common questions
What happens when Enhance MD's promotional price ends?
The ongoing flat rate is higher than the $49 introductory month and is not prominently published before intake. Ask for it before the first charge, since it governs almost the entire cost of a year of treatment.
Is Enhance MD cheaper than Hers?
Yes, on the ongoing rate. Enhance MD runs $49/mo once promotional pricing ends, against $149/mo at Hers — a difference of 3.0x. Compare the first-month offers separately, because both providers discount entry differently from the rate you will actually be paying by month three.
Which has more patient reviews, Hers or Enhance MD?
Enhance MD, with 10,482 against 6,200. Ratings across this market cluster tightly, so volume is the more useful signal: it indicates how much operational load the platform has already absorbed, not how good the medication is.
Do Hers and Enhance MD prescribe the same medication?
No. Hers dispenses brand-name, FDA-approved finished medication; Enhance MD dispenses compounded medication prepared by a pharmacy rather than manufactured under an approved application. That is a regulatory difference rather than a branding one, and it is the main reason the two prices are not directly comparable.
Can I switch from Hers to Enhance MD later?
You can, and people do — usually when an introductory price expires. Budget for a repeat intake and a short overlap in supply, and confirm what happens to any unused portion of a multi-month plan before you cancel it.
The verdict
Enhance MD is the cheaper of the two to run at $49/mo, but a full-year total is only computable for one side of this comparison, so treat that as a directional finding rather than a settled one.
Hers's case is brand-name Wegovy at a price that usually buys compounded medication elsewhere; its cost: there is no compounded tier to fall back on if the brand-name price stops working for you.
Get the maintenance-dose price in writing from whichever one you pick. That single question prevents most of the regret in this category.
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Disclaimers and methodology
Medical content is informational only and does not replace professional diagnosis, treatment, or emergency care.
Some links are affiliate links and may generate commission at no extra cost to you.
Pricing reflects what each provider published as of the sync date above and changes frequently; confirm the current rate, and the rate at your maintenance dose, before you pay. Six- and twelve-month totals are calculated from those published rates and exclude anything a provider bills separately.
eRxDoctor is an independent publisher. It is not a medical provider, is not affiliated with or endorsed by Hers or Enhance MD, and does not sell treatment. Read our ranking methodology.