Budget vs premium
Yucca Health vs MedVi: Which Costs Less Over 12 Months? (2026)
Yucca Health costs $1,752 a year against $3,468 for MedVi. Full 2026 comparison of price, medication class and included support.
Published · Pricing as published in our provider dataset, synced · Editorial scores 9.5 and 9.2 out of 10
We may receive compensation when you click partner links. Rankings are based on research methodology, not sponsorship.
MedVi and Yucca Health both promise a fast route to GLP-1 treatment without an office visit. What they promise afterward is where they separate.
MedVi costs 2.0x more per month than Yucca Health once promotional pricing is out of the picture ($299/mo against $146/mo). Over a year that gap compounds into real money, and the question is what it buys.
The sections that follow price both programs across a full course of treatment rather than a first month, then set out which patient each one is actually built for. Anything a provider declines to disclose is marked undisclosed rather than filled in.
The short answer
- Lowest 12-month cost
- Yucca Health — $1,752 against $2,592 at MedVi, on each provider's own best published pricing.
- Most predictable bill
- Yucca Health — Price locked for the life of the plan, so titration does not change what you are charged.
- Tirzepatide access
- Yucca Health — Tirzepatide at $258/mo; the other side publishes semaglutide only.
- Widest medication choice
- Yucca Health — compounded semaglutide and compounded tirzepatide.
Side-by-side comparison
The table is built from each provider's published pricing and program detail; anything they decline to state is marked as such.
| Yucca Health | MedVi | |
|---|---|---|
| Advertised price | Semaglutide $146/mo, tirzepatide $258/mo | $179 promotional first month |
| Rate after promotions | $146/mo | $299/mo |
| Pricing structure | Price locked for the life of the plan | Promotional first month, then standard rate |
| Medication | Compounded semaglutide and compounded tirzepatide | Compounded semaglutide |
| How fast you start | Approval within 24 hours | Simple online process, no clinic visits |
| State coverage | All 50 states | Not published |
| Payment options | Klarna, Afterpay and Affirm | Card only, no financing published |
| Membership fee | None | None |
| Patient reviews | 36,958 | 12,896 |
| eRxDoctor score | 9.5/10 | 9.2/10 |
Cost over a full course of treatment
GLP-1 treatment is not a one-month purchase, and neither of these prices it like one. Below, both are carried out to six and twelve months so the comparison holds at the point it matters.
| Yucca Health | MedVi | |
|---|---|---|
| First month | $146 | $179 |
| Months 2 onward | $146/mo | $299/mo |
| 6-month total | $876 | $1,674 |
| 12-month total | $1,752 | $3,468 |
| Best published plan | 6-month semaglutide plan at $875 — $1,752/yr | 3-month plan at $649 — $2,592/yr |
Yucca Health finishes the year $840 cheaper. For some patients the support MedVi bundles closes that gap; for a patient who only needs the prescription written, it does not.
Price escalation to plan for: MedVi moves from $179 to $299, a 67% increase. Set a calendar reminder for the month it changes.
Where the extra money goes at MedVi
Before treating the cheaper option as the obvious one, it is worth naming what the more expensive one includes — at MedVi that is 24/7 support from certified medical professionals, plus fast, free shipping.
On the other side, Yucca Health leads with a price lock at $146 plus three buy-now-pay-later options, which is unusual at the bottom of the market — with one qualification: no branded medication, no insurance billing and no outcome guarantee.
For a patient who has taken a GLP-1 before, knows how they titrate and needs a reliable monthly refill, the cheaper program is usually the correct one and the premium is a donation. For a first prescription, the calculus changes.
Yucca Health in detail
The pitch is a price lock at $146 plus three buy-now-pay-later options, which is unusual at the bottom of the market. Yucca Health (TryYucca) review 2026: personalized compounded semaglutide from $146/month and tirzepatide from $258/month. Fast 24-hr approval, UPS 2-Day Air, Klarna/Affirm/Afterpay accepted.
Practically: approval within 24 hours, UPS 2-Day Air from a licensed U.S. compounding pharmacy, and a pricing model that is price locked for the life of the plan.
Personalized treatment plans from board-certified providers. The formulary covers compounded semaglutide and compounded tirzepatide.
Yucca Health pros
- 6-month semaglutide plan at $875 locks in the best per-month rate
- Three Buy Now Pay Later options: Klarna, Afterpay, and Affirm
- Compounded semaglutide from $146/month, one of the lowest prices from a legitimate GLP-1 telehealth provider
- Compounded tirzepatide from $258/month, dual GIP/GLP-1 mechanism for higher average weight loss
Yucca Health cons
- Cancellation terms for multi-month plans should be confirmed before purchase
- No weight loss warranty or outcome guarantee
- Does not accept health insurance
Where it gives ground to MedVi: no branded medication, no insurance billing and no outcome guarantee.
Inside the MedVi program
MedVi provides compounded semaglutide starting at $179/month with a simple online intake, no clinic visits, and 24/7 certified medical support for weight loss. In this pairing, its distinguishing feature is a genuinely low promotional entry point with 24/7 clinical support behind it.
Intake is simple online process, no clinic visits. Fulfillment is fast, free shipping. The commercial terms are promotional first month, then standard rate, published upfront.
Support: 24/7 support from certified medical professionals. The medications on offer are compounded semaglutide.
MedVi pros
- Simple online process with no clinic visits required
- 24/7 support from certified medical professionals
- Clinically dosed compounded semaglutide
- Low promotional first month at $179 including fast, free shipping
MedVi cons
- Compounded medication only, no branded Ozempic or Wegovy
- No published outcome or weight loss guarantee
- Price increases sharply after the first month, $299 for a standalone month
Read next to Yucca Health, the weak point: the price roughly doubles to $299 once the promotional month ends.
Yucca Health or MedVi: matching the program to the patient
Choose Yucca Health if:
- the level of clinical contact suits you: personalized treatment plans from board-certified providers
- you want to start on their timeline: approval within 24 hours
- the twelve-month total is what you are optimizing ($1,752 against $3,468)
- what it leads on is worth paying for in your case: a price lock at $146 plus three buy-now-pay-later options, which is unusual at the bottom of the market
Choose MedVi if:
- delivery works the way you want it to: fast, free shipping
- you want to start on their timeline: simple online process, no clinic visits
- the level of clinical contact suits you: 24/7 support from certified medical professionals
- the feature you would actually use: a genuinely low promotional entry point with 24/7 clinical support behind it
The compromises on both sides
On price. $146/mo against $299/mo. MedVi is asking you to pay for a genuinely low promotional entry point with 24/7 clinical support behind it; decide whether that is a line item you will use.
On commitment. Yucca Health rewards a longer commitment (6-month semaglutide plan at $875), which lowers the effective rate but ties up money before you know how you respond to the medication. Financing is available through Yucca Health (Klarna, Afterpay and Affirm).
On access. Yucca Health advertises approval within 24 hours and UPS 2-Day Air from a licensed U.S. compounding pharmacy; MedVi advertises simple online process, no clinic visits and fast, free shipping. Coverage differs too — all 50 states against not published — which decides the question before price does if you are in a restricted state.
On predictability. The pricing structures differ (price locked for the life of the plan versus promotional first month, then standard rate), and structure, not headline rate, determines the twelve-month bill.
What the trials and the FDA say
Neither Yucca Health nor MedVi manufactures the molecule it prescribes, and the clinical evidence behind GLP-1 treatment belongs to the drug rather than to any platform selling access to it.
The NIH position is that weight-management medication works alongside changes in eating and activity, not instead of them, per NIH, NIDDK.
Compounding is lawful within a specific statutory framework, and the conditions attached to it have changed as GLP-1 shortages have resolved, per FDA.
Take the clinical questions to the prescribing clinician at whichever platform you choose; take the pricing questions to their support team before you pay.
Yucca Health vs MedVi: common questions
What happens when MedVi's promotional price ends?
The rate moves to $299/mo, a 67% increase on the advertised entry price. Budget from that number rather than the headline, because it is the one you will pay for eleven of your first twelve months.
Which is cheaper to start, Yucca Health or MedVi?
Yucca Health, at $146 against $179. Note that the cheapest first month and the cheapest year are often different providers here — check the 12-month row of the cost table before deciding on the entry price.
Which has more patient reviews, Yucca Health or MedVi?
Yucca Health, with 36,958 against 12,896. Ratings across this market cluster tightly, so volume is the more useful signal: it indicates how much operational load the platform has already absorbed, not how good the medication is.
Do Yucca Health or MedVi take insurance?
Both run on a direct-pay basis: you pay the platform and it does not bill your insurer. Neither publishes HSA/FSA acceptance, so budget the full amount as out-of-pocket spending.
How fast can I start with Yucca Health compared with MedVi?
Yucca Health advertises approval within 24 hours, with UPS 2-Day Air from a licensed U.S. compounding pharmacy. MedVi advertises simple online process, no clinic visits, with fast, free shipping. Both are subject to clinician review and to whether your state and health history clear, so treat the advertised timeline as a best case rather than a commitment.
The verdict
Strictly on cost, Yucca Health takes it — $1,752 to $2,592 over twelve months.
The case for MedVi is a genuinely low promotional entry point with 24/7 clinical support behind it. That is worth $70 a month to some patients and nothing at all to others — be honest about which you are.
Neither choice is irreversible. Start with the program whose weaknesses you can tolerate, and reassess at month three when you know how you respond to the medication.
Keep comparing
- Yucca Health vs NoviFinancing and HSA/FSA
- Yucca Health vs Mochi HealthLocked price vs escalating price
- Hers vs MedViBrand-name vs compounded
- TrimRx vs MedViBudget vs premium
- Measured vs GalaBudget vs premium
- Enhance MD vs MaximusBudget vs premium
See every provider in context on the weight loss rankings, or browse the full comparison index.
Disclaimers and methodology
Medical content is informational only and does not replace professional diagnosis, treatment, or emergency care.
Some links are affiliate links and may generate commission at no extra cost to you.
Pricing reflects what each provider published as of the sync date above and changes frequently; confirm the current rate, and the rate at your maintenance dose, before you pay. Six- and twelve-month totals are calculated from those published rates and exclude anything a provider bills separately.
eRxDoctor is an independent publisher. It is not a medical provider, is not affiliated with or endorsed by Yucca Health or MedVi, and does not sell treatment. Read our ranking methodology.