Program review
Signos review 2026: a CGM-guided weight loss program
Signos combines a continuous glucose monitor with an AI app to show how food, sleep and movement move your glucose. It costs $127/month with the sensor included, and it is a behavior-feedback program, not a prescription service.
Published · Pricing last checked October 2026 · Editorial score 8 out of 10
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The short answer
- Published price
- $127/mo Hardware is included. Pricing varies by plan and promotion, and the AUTUMN25 code advertised 25% off at the time of writing.
- What stands out
- Glucose-guided habits. Signos turns CGM readings, meal logs and workouts into daily prompts and metabolism scores.
- What to verify
- Which plan includes clinicians. Any GLP-1 access runs through independent clinicians and may be compounded, so confirm it before you enroll.
What is Signos?
Signos is a metabolic health platform that pairs an over-the-counter, FDA-cleared continuous glucose monitor with an AI-powered app. The sensor sends glucose data to the app, which combines it with your logged meals, workouts and other habits to predict responses and suggest what to do next.
The company’s argument is that frequent glucose spikes make weight loss harder and steadier glucose supports it. That makes Signos a coaching tool first. If you want medication, compare Measured or Hers; if you want to learn your own patterns, Signos is the more direct fit.
How Signos works
- Choose a Signos CGM plan; the membership includes the sensor hardware.
- Wear the sensor and open the app on a compatible smartphone (not included).
- Log meals, workouts and sleep, and sync Apple Health, Google Health Connect, smartwatches or smart scales.
- Follow prompts around meals, movement and sleep, and track daily and weekly Metabolism Scores.
When something you eat spikes your glucose, the app can suggest the type and intensity of movement, based on your history, to help bring it back down.
Signos pricing and what is included
Signos lists $127/month with hardware included, and a lighter Signos Essentials plan also exists. The comparison table is Signos’s own estimate of piecing a system together yourself, so read it as marketing rather than a quote.
| Item | Signos membership | On your own (per Signos) |
|---|---|---|
| Monthly cost | $127/month | $800+/month |
| Continuous glucose monitors | Included | $100/month |
| Registered dietitian support | Included | $200+/hour |
| Metabolic insights | Included | $100/month (multiple apps) |
| 30-day results guarantee | Included | Not applicable |
The guarantee is narrow: if you do not learn something new about how your body loses weight, a Senior Signos Coach will audit your data for free (a $250 value). It is not a refund promise.
Pros and cons
What Signos does well
- Hardware included in the $127/month membership
- FDA-cleared CGM system with no diabetes diagnosis needed
- Registered dietitian support included
- HSA/FSA eligible, subject to your plan administrator
- 30-day results guarantee
What to confirm first
- It is not a medication and will not suppress appetite
- Not for people on insulin or with problematic hypoglycemia
- About 20% of sensors may not last the full 15 days
- Success figures are member-reported, not trial data
- Medication access runs through independent clinicians and may be compounded
Who Signos is for
Signos fits adults who are not on insulin, are comfortable wearing a sensor, and want data about how meals and habits affect them, especially after calorie counting stopped working. If you already know you want prescription medication, altRx is the shorter path. Signos is not for anyone who expects the app to work without changes to food and movement.
Evidence and safety
The research Signos cites is a Clinical Diabetes review of CGMs as behavior-modification tools. It supports the idea that glucose feedback can change food and activity choices. It does not show that Signos produces a particular amount of weight loss.
If an associated clinician offers a compounded GLP-1, the FDA explains that compounded drugs are not FDA-approved. Do not change any medication based on sensor readings without consulting your clinician.
This page does not diagnose, prescribe, or establish eligibility.
The verdict
Signos is the right pick for a data-minded person who wants to know why a meal left them crashing and what to change. At $127/month with the sensor included it is priced as a program. It will not replace medication for people who need it, and its results claims are company-reported. Our score: 8/10.
Signos: common questions
Is Signos worth it for weight loss?
Signos is worth considering if you want to see how your own meals, sleep and movement affect your glucose and you will wear the sensor consistently. Its 86% first-month success figure is member-reported data from consistent users, so treat it as company data rather than clinical evidence. It is a feedback tool, not a medication.
How much does Signos cost?
Signos lists its membership at $127/month with the continuous glucose monitor hardware included. Pricing varies by plan and promotion, and the code AUTUMN25 for 25% off was advertised at the time of writing. Confirm current pricing on the Signos plans page.
Does Signos prescribe GLP-1 medication?
Signos says clinical services accessible through its platform come from OpenLoop Health and other independent U.S.-licensed clinicians, who decide GLP-1 eligibility and may prescribe or decline compounded medication. Signos does not itself practice medicine or dispense medication. Ask which plan includes medication before enrolling.
Do I need diabetes to use Signos?
No. The Signos system is intended for adults 18 and older who are not on insulin. It is not intended to guide medical action without a qualified healthcare professional.
How long do Signos sensors last?
Sensors are designed to last 15 days. Signos cites a study in which 77.9% of sensors lasted the full 15 days, so some sensors will not.
Can I pay for Signos with an HSA or FSA?
Signos advertises HSA/FSA eligibility, but coverage depends on your plan administrator. Its cancellation policy and terms apply even if reimbursement is denied.
Keep comparing
See how the rest of the market prices the same treatment on the weight loss rankings, or read the head-to-head articles in the comparison index.
Disclaimers and methodology
Medical content is informational only and does not replace professional diagnosis, treatment, or emergency care.
Some links are affiliate links and may generate commission at no extra cost to you.
Pricing and feature statements reflect Signos materials reviewed on October 9, 2026 and can change without notice. The published price is $127/mo; it is not a guarantee of eligibility, availability or the final recurring charge.
eRxDoctor is an independent publisher. It is not a medical provider, is not affiliated with or endorsed by Signos, and does not sell treatment. Read our ranking methodology.