Coaching-supported vs medication-only
Novi vs He & She MD: Coaching Included, or Just a Script? (2026)
Novi or He & She MD? Side-by-side 2026 pricing, medication and service comparison, extended to six and twelve-month totals.
Published · Pricing as published in our provider dataset, synced · Editorial scores 7.0 and 7.0 out of 10
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The choice between Novi and He & She MD usually comes down to one difference that neither homepage puts in its headline.
One of these programs is a prescription; the other is a prescription plus a support structure. He & She MD includes coaching app with 1:1 clinician messaging and progress tracking, no extra charge, while Novi is deliberately a medication-only service at a medication-only price.
The comparison below starts from published pricing, converts it into annual cost, and then asks what the more expensive side is delivering for the difference. Gaps in a provider's disclosure are reported as gaps, because they are part of what you are buying.
The short answer
- Lowest 12-month cost
- Novi — $1,596 against $1,980 at He & She MD, on each provider's own best published pricing.
- Most support for the money
- He & She MD — Coaching app with 1:1 clinician messaging and progress tracking, no extra charge.
- Quickest to start
- Novi — Online intake, then free 2-day shipping with every order.
- Easiest to pay for
- Novi — Neither publishes financing; both expect the full amount monthly.
Novi vs He & She MD at a glance
The rows below are the ones that differ enough between these two to be worth your attention.
| Novi | He & She MD | |
|---|---|---|
| Advertised price | Semaglutide from $133/mo, tirzepatide from $166/mo | Semaglutide from $139/mo, oral semaglutide and tirzepatide from $199/mo |
| Rate after promotions | $133/mo | $191/mo |
| Pricing structure | Published rate per medication | Introductory term, then renewal at a higher rate |
| Medication | Compounded semaglutide and compounded tirzepatide | Compounded semaglutide injection, oral semaglutide and compounded tirzepatide injection |
| Support model | No coaching program stated | Coaching built into the plan |
| Membership fee | None | None |
| How fast you start | Online intake | 2-3 minute intake with no payment required to check eligibility |
| State coverage | Not published | Not published |
| Price transparency | Published upfront | Published upfront |
| Patient reviews | 50,124 | 4,180 |
| eRxDoctor score | 7.0/10 | 7.0/10 |
The real cost: six months and twelve
Comparing entry prices across these two would be actively misleading, because they escalate differently. The totals below are the honest version, built from the rates each provider publishes.
| Novi | He & She MD | |
|---|---|---|
| First month | $133 | $139 |
| Months 2 onward | $133/mo | $191/mo |
| 6-month total | $798 | $834 |
| 12-month total | $1,596 | $1,980 |
| Best published plan | No multi-month discount published | No multi-month discount published |
The twelve-month spread is $384. That is the number to hold He & She MD against: it has to justify roughly $32 extra every month.
Price escalation to plan for: He & She MD moves from $139 to $191, a 37% increase. Set a calendar reminder for the month it changes.
Coaching, or just the prescription
He & She MD includes coaching app with 1:1 clinician messaging and progress tracking, no extra charge. That is a real cost to deliver, and it is priced into the monthly rate whether or not you open the app.
Novi is built the other way: no long-term contract, cancel anytime. The medication does the pharmacological work, and everything around it is yours to organize.
Coaching is the line item people cancel first and miss most. Be honest about which patient you are before optimizing it away.
Novi: what you are buying
$200 OFF - GLP-1 for $133 Today What it is really selling here is the narrowest gap here between semaglutide and tirzepatide pricing, at $133 and $166.
Getting started means online intake, after which free 2-day shipping with every order. Pricing runs on a published rate per medication basis, published upfront.
Ongoing care is no long-term contract, cancel anytime, and the medication list runs to compounded semaglutide and compounded tirzepatide.
Novi pros
- No insurance required and no long-term contract, cancel anytime
- $200 off promotion brings GLP-1 to $133 today
- Largest patient base on this list, 50,000+ patients, signaling operational maturity
- Competitive pricing: semaglutide from $133/month and tirzepatide from $166/month
Novi cons
- Tirzepatide ($166) costs more than the semaglutide entry rate
- Compounded medication only, no branded Ozempic, Wegovy, or Zepbound
- No published outcome or weight loss guarantee
Where it gives ground to He & She MD: the $133 rate depends on a $200-off promotion and there is no outcome guarantee.
A closer look at He & She MD
He & She MD bundles compounded GLP-1 medication with a coaching app that carries 1:1 clinician messaging, GLP-1-specific guidance and progress tracking. Semaglutide injections start at $139/month, oral semaglutide and tirzepatide at $199/month, each a six-month introductory rate. Free expedited shipping, no membership fee, no insurance required. In this pairing, its distinguishing feature is three medication formats and a coaching app included, under a named board-certified obesity-medicine CMO.
Intake is 2-3 minute intake with no payment required to check eligibility. Fulfillment is free expedited shipping with no upcharges. The commercial terms are introductory term, then renewal at a higher rate, published upfront.
Support: coaching app with 1:1 clinician messaging and progress tracking, no extra charge. The medications on offer are compounded semaglutide injection, oral semaglutide and compounded tirzepatide injection.
He & She MD pros
- Three formats: semaglutide injection, oral semaglutide, tirzepatide injection
- Coaching app, 1:1 clinician messaging and progress tracking included at no extra cost
- Named, dual board-certified obesity-medicine Chief Medical Officer
- $139/mo intro price is competitive for a program with this much bundled support
He & She MD cons
- Headline prices are 6-month intro rates that renew 30-45% higher
- Pricing is structured as six-month terms, not true month-to-month
- Compounded GLP-1s are not reviewed by the FDA for safety, efficacy or quality
Set beside Novi, the thing to weigh: the headline rates are six-month terms that renew 30-45% higher.
Picking between them
Choose Novi if:
- the monthly rate is the constraint — $133/mo against $191/mo
- you would rather use the platform with the longer public record (50,124 reviews)
- the twelve-month total is what you are optimizing ($1,596 against $1,980)
- what it leads on is worth paying for in your case: the narrowest gap here between semaglutide and tirzepatide pricing, at $133 and $166
Choose He & She MD if:
- delivery works the way you want it to: free expedited shipping with no upcharges
- you want to start on their timeline: 2-3 minute intake with no payment required to check eligibility
- the level of clinical contact suits you: coaching app with 1:1 clinician messaging and progress tracking, no extra charge
- what it leads on is worth paying for in your case: three medication formats and a coaching app included, under a named board-certified obesity-medicine CMO
The compromises on both sides
On price. The monthly gap is 44% in Novi's favor. Whether that is a saving or a false economy turns on one thing: the $133 rate depends on a $200-off promotion and there is no outcome guarantee.
On commitment. Neither publishes a multi-month discount, so both are month-to-month decisions and neither asks you to prepay for a response you have not had yet. Neither publishes financing options, so plan for the full amount each month.
On clinical contact. No long-term contract, cancel anytime at Novi; coaching app with 1:1 clinician messaging and progress tracking, no extra charge at He & She MD. Neither is a substitute for in-person care if you have complicating conditions, and both bill you directly rather than your insurer.
On medication. Novi covers compounded semaglutide and compounded tirzepatide; He & She MD covers compounded semaglutide injection, oral semaglutide and compounded tirzepatide injection. Neither locks you out of a molecule the other offers, so this is unlikely to be the deciding factor.
Evidence and regulatory status
It is worth separating the program from the pharmacology. What follows is true of the medication regardless of which of these two writes the prescription.
The FDA publishes an ongoing record of semaglutide products marketed for diabetes and weight loss, and which of them it has actually approved, per FDA.
Dosing errors are the failure mode the FDA has flagged most often with unapproved GLP-1 products, particularly where a patient draws the dose themselves, per FDA.
Neither platform's marketing changes any of that. It is the same evidence base whichever one takes your card.
Novi vs He & She MD: common questions
Which is cheaper to start, Novi or He & She MD?
Novi, at $133 against $139. Note that the cheapest first month and the cheapest year are often different providers here — check the 12-month row of the cost table before deciding on the entry price.
How fast can I start with Novi compared with He & She MD?
Novi advertises online intake, with free 2-day shipping with every order. He & She MD advertises 2-3 minute intake with no payment required to check eligibility, with free expedited shipping with no upcharges. Both are subject to clinician review and to whether your state and health history clear, so treat the advertised timeline as a best case rather than a commitment.
Do Novi or He & She MD take insurance?
Both run on a direct-pay basis: you pay the platform and it does not bill your insurer. Neither publishes HSA/FSA acceptance, so budget the full amount as out-of-pocket spending.
Are Novi and He & She MD legitimate?
Both are licensed telehealth platforms that route a prescription through a clinician review before anything is dispensed; neither sells medication without one. Novi operates on published rate per medication with pricing published upfront, He & She MD on introductory term, then renewal at a higher rate, published upfront. The meaningful due diligence is on the medication category and the terms, not on whether the platforms are real.
Is Novi or He & She MD better for a first GLP-1 prescription?
If this is your first GLP-1, the question is who answers when nausea arrives on day nine. He & She MD publishes coaching app with 1:1 clinician messaging and progress tracking, no extra charge, which is the more useful thing to buy at the start.
What happens if I stop taking the medication?
Both programs are month to month, which makes stopping easy and makes the consequence of stopping the thing to plan for: published extension data shows most of the lost weight returns within about a year. That is an argument for choosing on annual cost rather than entry price.
The verdict
On the numbers, Novi wins the year: $1,596 against $1,980. That is the default answer, and it is the right one for anyone who mainly needs a reliable prescription and a shipment that arrives.
Where He & She MD justifies itself is three medication formats and a coaching app included, under a named board-certified obesity-medicine CMO. Where it does not is anywhere the extra spend buys features you will never open.
The failure mode here is not picking the wrong platform; it is stopping treatment because the bill moved. Choose the one whose bill you can predict.
Keep comparing
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- Mochi Health vs He & She MDBudget vs premium
- Elevate Health vs He & She MDCoaching-supported vs medication-only
- Measured vs RefillsCoaching-supported vs medication-only
- Wellmedr vs MeasuredCoaching-supported vs medication-only
See every provider in context on the weight loss rankings, or browse the full comparison index.
Disclaimers and methodology
Medical content is informational only and does not replace professional diagnosis, treatment, or emergency care.
Some links are affiliate links and may generate commission at no extra cost to you.
Pricing reflects what each provider published as of the sync date above and changes frequently; confirm the current rate, and the rate at your maintenance dose, before you pay. Six- and twelve-month totals are calculated from those published rates and exclude anything a provider bills separately.
eRxDoctor is an independent publisher. It is not a medical provider, is not affiliated with or endorsed by Novi or He & She MD, and does not sell treatment. Read our ranking methodology.