Budget vs premium
Enhance MD vs Sprout Health: Which Costs Less Over 12 Months? (2026)
Enhance MD $49/mo vs Sprout Health $249/mo. 2026 comparison of pricing, medication and support, with 12-month totals rather than first-month offers.
Published · Pricing as published in our provider dataset, synced · Editorial scores 8.4 and 7.4 out of 10
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Comparing Enhance MD with Sprout Health means comparing two business models more than two medications. The molecules overlap; the terms do not.
The gap is 5.1x: $49/mo at Enhance MD, $249/mo at Sprout Health. Neither number is unusual for the market, but paying the higher one only makes sense if you can name what it adds.
Rather than restate two feature lists, this compares the two on cost over time, medication access, price stability and the support each one includes. Where a figure is not published, that is stated rather than estimated.
The short answer
- Lowest ongoing rate
- Enhance MD — $49/mo against $249/mo, though only one of the two publishes enough to total a full year.
- Most predictable bill
- Enhance MD — Flat rate at every dose, so titration does not change what you are charged.
- Tirzepatide access
- Enhance MD — Tirzepatide at $99/mo; the other side publishes semaglutide only.
- Longest public track record
- Sprout Health — 14,569 patient reviews against 10,482.
Enhance MD vs Sprout Health at a glance
Two programs, side by side, on their own published terms — with the rows that differ doing the work.
| Enhance MD | Sprout Health | |
|---|---|---|
| Advertised price | Semaglutide from $49, tirzepatide from $99, first month | $199 first month with $50 off, then $249/mo |
| Rate after promotions | $49/mo | $249/mo |
| Pricing structure | Flat rate at every dose | Promotional first month, then standard rate |
| Medication | Compounded semaglutide and compounded tirzepatide | Compounded GLP-1 |
| Membership fee | Not stated | None |
| Payment options | Card only, no financing published | Card only, no financing published |
| State coverage | Not published | Not published |
| How fast you start | Online intake | Lightning-quick approval |
| Patient reviews | 10,482 | 14,569 |
| eRxDoctor score | 8.4/10 | 7.4/10 |
The real cost: six months and twelve
A first-month price is a customer-acquisition number. What matters is the total at the point most people are still in treatment, so both programs are extended to six and twelve months below.
| Enhance MD | Sprout Health | |
|---|---|---|
| First month | $49 | $199 |
| Months 2 onward | Not published | $249/mo |
| 6-month total | Not computable | $1,444 |
| 12-month total | Not computable | $2,938 |
| Best published plan | No multi-month discount published | No multi-month discount published |
A like-for-like annual total is not available for Enhance MD: the ongoing flat rate is higher than the $49 introductory month and is not prominently published before intake. Treat any comparison that quotes one as an estimate someone else has made for you.
Price escalation to plan for: Sprout Health moves from $199 to $249, a 25% increase. Set a calendar reminder for the month it changes.
Enhance MD is cheaper. Does that make it better?
The gap runs to 5.1x a month. What Sprout Health offers for it: fast, hassle-free GLP-1 delivery, plus home delivery.
Enhance MD counters with the lowest first month anywhere on this list, on both compounds, and the thing it asks you to accept in return: what you pay in month two is the number that is missing.
The premium buys attention. If you expect to need it — first GLP-1, side effects you will want triaged quickly, a history of stalling around week ten — it is money well spent. If you do not, it is not.
A closer look at Enhance MD
Enhance MD offers semaglutide from $49 and tirzepatide from $99 for your first month, with flat-rate pricing that stays the same at every dose, no fee escalation. Against Sprout Health, that puts it in the position of the cheaper option.
Intake is online intake. Fulfillment is home delivery. The commercial terms are flat rate at every dose, partly published.
Support: 10,000+ patients treated. The medications on offer are compounded semaglutide and compounded tirzepatide.
Enhance MD pros
- 10,000+ patients treated, meaningful real-world clinical volume
- Both semaglutide and tirzepatide available on one platform
- Flat-rate pricing: the same price at every dose, with no fee escalation during titration
- Cheapest first month for both compounds, semaglutide from $49 and tirzepatide from $99
Enhance MD cons
- Ongoing flat-rate pricing not always prominently published before intake
- The $49/$99 rates are first-month introductory prices; ongoing flat rate is higher
- Compounded medication only, no branded Ozempic, Wegovy, or Zepbound
Read next to Sprout Health, the weak point: what you pay in month two is the number that is missing.
How Sprout Health works
Sprout Health positions itself on a no-frills route to a first injection for people who want to start this week. Special Offer: Get $50 Off Your First Month
Getting started means lightning-quick approval, after which home delivery. Pricing runs on a promotional first month, then standard rate basis, published upfront.
Fast, hassle-free GLP-1 delivery. The formulary covers compounded GLP-1.
Sprout Health pros
- Clear outcome framing, 10–26% body weight loss over 12 months
- Fully online with fast, hassle-free GLP-1 medication delivery
- $50 off the first month, bringing it to $199
- Lightning-quick approval process
Sprout Health cons
- No published outcome guarantee despite the outcome-focused marketing
- Compounded medication only, no branded Ozempic or Wegovy
- Higher ongoing cost than several competitors
Where it gives ground to Enhance MD: $249 a month ongoing is above the market and the outcome framing is marketing, not a guarantee.
Which one fits which patient
Choose Enhance MD if:
- you want the price you sign up at to survive titration
- the monthly rate is the constraint — $49/mo against $249/mo
- the feature you would actually use: the lowest first month anywhere on this list, on both compounds
- you want tirzepatide available without changing provider later
Choose Sprout Health if:
- you want to start on their timeline: lightning-quick approval
- the level of clinical contact suits you: fast, hassle-free GLP-1 delivery
- what it leads on is worth paying for in your case: a no-frills route to a first injection for people who want to start this week
- you want the full price in front of you before completing an intake
Honest trade-offs
On price. The monthly gap is 5.1x in Enhance MD's favor. Whether that is a saving or a false economy turns on one thing: what you pay in month two is the number that is missing.
On commitment. Neither publishes a multi-month discount, so both are month-to-month decisions and neither asks you to prepay for a response you have not had yet. Neither publishes financing options, so plan for the full amount each month.
On medication. Enhance MD covers compounded semaglutide and compounded tirzepatide; Sprout Health covers compounded GLP-1. Only Enhance MD publishes a tirzepatide route, which matters if semaglutide underdelivers.
On clinical contact. The support models differ — 10,000+ patients treated against fast, hassle-free GLP-1 delivery — and that difference is felt in week two, not week one.
What the evidence actually says
Weight loss percentages quoted in telehealth marketing come from trials neither Enhance MD nor Sprout Health ran. Here is the source material, and what regulators say alongside it.
NIDDK frames medication as one component of obesity treatment rather than a replacement for the rest of it, per NIH, NIDDK.
SURMOUNT-4 found that continuing tirzepatide maintained and extended weight reduction, while withdrawing it led to substantial regain, per JAMA, SURMOUNT-4.
Which is to say: the medication decision belongs with a clinician, and the platform decision belongs with a spreadsheet.
Enhance MD vs Sprout Health: common questions
Which is cheaper to start, Enhance MD or Sprout Health?
Enhance MD, at $49 against $199. Note that the cheapest first month and the cheapest year are often different providers here — check the 12-month row of the cost table before deciding on the entry price.
Are Enhance MD and Sprout Health legitimate?
Both are licensed telehealth platforms that route a prescription through a clinician review before anything is dispensed; neither sells medication without one. Enhance MD operates on flat rate at every dose with pricing partly published, Sprout Health on promotional first month, then standard rate, published upfront. The meaningful due diligence is on the medication category and the terms, not on whether the platforms are real.
What happens if I stop taking the medication?
Neither Enhance MD nor Sprout Health penalizes you for stopping, but the medication does. The published follow-up data on withdrawal shows substantial regain, which is why the twelve-month totals above matter more than either provider's introductory offer.
Is Enhance MD or Sprout Health better for a first GLP-1 prescription?
First-timers usually get more from clinical access than from a lower rate, because the first two months are where most people stop. On that basis Enhance MD has the stronger case; after month three, cost should take over.
Can I switch from Enhance MD to Sprout Health later?
Yes. Neither program locks you in clinically, and both operate month to month unless you have bought a multi-month plan. Practically, switching means a fresh intake, a fresh clinician review and possibly a gap in supply, so time it against your current shipment rather than your renewal date.
Does Enhance MD or Sprout Health offer tirzepatide?
Enhance MD does, at $99/mo. Sprout Health publishes compounded GLP-1 only, so moving to tirzepatide would mean moving provider — a new intake, a new price, and the loss of any rate you had locked in.
Do Enhance MD and Sprout Health prescribe the same medication?
Both dispense compounded GLP-1 preparations. Enhance MD lists compounded semaglutide and compounded tirzepatide and Sprout Health lists compounded GLP-1, so the molecules overlap even where the formulary does not match exactly.
The verdict
Enhance MD is the cheaper of the two to run at $49/mo, but a full-year total is only computable for one side of this comparison, so treat that as a directional finding rather than a settled one.
Sprout Health's case is a no-frills route to a first injection for people who want to start this week; its cost: $249 a month ongoing is above the market and the outcome framing is marketing, not a guarantee.
Get the maintenance-dose price in writing from whichever one you pick. That single question prevents most of the regret in this category.
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Disclaimers and methodology
Medical content is informational only and does not replace professional diagnosis, treatment, or emergency care.
Some links are affiliate links and may generate commission at no extra cost to you.
Pricing reflects what each provider published as of the sync date above and changes frequently; confirm the current rate, and the rate at your maintenance dose, before you pay. Six- and twelve-month totals are calculated from those published rates and exclude anything a provider bills separately.
eRxDoctor is an independent publisher. It is not a medical provider, is not affiliated with or endorsed by Enhance MD or Sprout Health, and does not sell treatment. Read our ranking methodology.