Published price vs quote-only
Directmeds vs Refills: Which One Publishes Its Price? (2026)
Directmeds quotes after intake, Refills $99/mo. What each 2026 program includes, what it omits, and which patient each one suits.
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Refills and Directmeds both promise a fast route to GLP-1 treatment without an office visit. What they promise afterward is where they separate.
One of these programs can be evaluated before you start it and one cannot. Refills lists GLP-1 from $99/mo, about $5 a day; with Directmeds, standard post-promotional pricing is not disclosed upfront.
Each program is read on its own published terms first, then against the other on the four things that decide satisfaction: price, predictability, formulary and access to a clinician. Anything a provider declines to disclose is marked undisclosed rather than filled in.
The short answer
- Easier to price in advance
- Refills — GLP-1 from $99/mo, about $5 a day. The other side quotes after intake, so a like-for-like total is not available before you apply.
- Most predictable bill
- Refills — Flat rate at every dose, so titration does not change what you are charged.
- Tirzepatide access
- Refills — The only one of the two that publishes a dual GIP/GLP-1 option.
- Widest medication choice
- Refills — compounded semaglutide and GIP+GLP-1 dual agonist.
Side-by-side comparison
Scan the pricing rows first, then the medication row. Those two settle most of these decisions between them.
| Directmeds | Refills | |
|---|---|---|
| Advertised price | 50% off the first month | GLP-1 from $99/mo, about $5 a day |
| Rate after promotions | not published before intake | $99/mo |
| Pricing structure | Quoted only after intake | Flat rate at every dose |
| Medication | GLP-1 medication via licensed telehealth prescribing | Compounded semaglutide and GIP+GLP-1 dual agonist |
| Price transparency | Quote only, after intake | Published upfront |
| Shipping | Nationwide shipping, no insurance required | Free, fast and discreet shipping on every order |
| Payment options | Card only, no financing published | Card only, no financing published |
| Tirzepatide | Not published | Available |
| Support model | No coaching program stated | No coaching program stated |
| Patient reviews | 3,400 | 7,400 |
| eRxDoctor score | 7.8/10 | 7.7/10 |
The real cost: six months and twelve
Both providers lead with a number designed to get you through the intake. The figures underneath convert both offers into what you will have spent by month six and month twelve.
| Directmeds | Refills | |
|---|---|---|
| First month | Not published | $99 |
| Months 2 onward | Not published | $99/mo |
| 6-month total | Not computable | $594 |
| 12-month total | Not computable | $1,188 |
| Best published plan | No multi-month discount published | No multi-month discount published |
A like-for-like annual total is not available for Directmeds: standard post-promotional pricing is not disclosed upfront. Treat any comparison that quotes one as an estimate someone else has made for you.
What each one will tell you before you commit
Refills publishes GLP-1 from $99/mo, about $5 a day before intake. That is the baseline condition for comparing two programs at all.
Directmeds withholds the figure until online intake is complete — standard post-promotional pricing is not disclosed upfront. Whatever the reason, it moves the price conversation to after your commitment rather than before it.
The workaround is straightforward: complete Directmeds's assessment, get the quote, and then price it against Refills's published $99/mo before agreeing to anything.
Inside the Directmeds program
Directmeds positions itself on a half-price first month and nationwide shipping with no insurance step. Directmeds is a licensed telehealth platform offering GLP-1 medications with a 50% first-month discount and nationwide shipping.
You start with online intake; medication arrives via nationwide shipping, no insurance required. The price behaves as quoted only after intake.
Ongoing care is licensed telehealth prescribing, and the medication list runs to GLP-1 medication via licensed telehealth prescribing.
Directmeds pros
- Licensed telehealth prescribing model
- 50% off first month for new patients
- Nationwide shipping, no insurance required
Directmeds cons
- Standard (post-promo) pricing is not clearly disclosed upfront
Where it gives ground to Refills: a discount off an undisclosed price is not a price.
Refills: what you are buying
Refills offers personalized compounded GLP-1 from $99/month (~$5/day) with flat pricing, the same price at every dosage, plus free discreet shipping, 24/7 health concierge support, and no membership or app fees.
From signup to first shipment: 3-minute approval quiz, then free, fast and discreet shipping on every order. Billing follows a flat rate at every dose structure.
Behind the prescription sits free 24/7 health concierge. Available medication: compounded semaglutide and GIP+GLP-1 dual agonist.
Refills pros
- No insurance required, 3-minute approval quiz
- LegitScript-certified U.S. compounding pharmacies with third-party USP testing
- Free 24/7 Health Concierge support
- Free, fast, and discreet shipping on every order
Refills cons
- Availability varies by state
- Compounded medication, not an FDA-approved branded product
- Clinicians come from partner telehealth networks (Beluga, Bask, Wasef Health)
Read next to Directmeds, the weak point: clinicians come from partner networks and availability varies by state.
Directmeds or Refills: matching the program to the patient
Choose Directmeds if:
- you want to start on their timeline: online intake
- delivery works the way you want it to: nationwide shipping, no insurance required
- the feature you would actually use: a half-price first month and nationwide shipping with no insurance step
- the level of clinical contact suits you: licensed telehealth prescribing
Choose Refills if:
- you want to start on their timeline: 3-minute approval quiz
- the level of clinical contact suits you: free 24/7 health concierge
- delivery works the way you want it to: free, fast and discreet shipping on every order
- you want tirzepatide available without changing provider later
The trade-offs, stated plainly
On price. Only Refills publishes a rate you can plan against (GLP-1 from $99/mo, about $5 a day). The other quotes after intake, which is a cost of a different kind: you cannot budget the year in advance.
On access. Directmeds advertises online intake and nationwide shipping, no insurance required; Refills advertises 3-minute approval quiz and free, fast and discreet shipping on every order. Coverage differs too — nationwide against availability varies by state — which decides the question before price does if you are in a restricted state.
On predictability. Quoted only after intake versus flat rate at every dose. Whichever you pick, get the maintenance-dose price in writing at intake.
On clinical contact. Licensed telehealth prescribing at Directmeds; free 24/7 health concierge at Refills. Neither is a substitute for in-person care if you have complicating conditions, and both bill you directly rather than your insurer.
Evidence and regulatory status
Before either program's marketing claims, the underlying evidence — which belongs to the medication, not the platform.
STEP 1 recorded a mean 14.9% reduction in body weight over 68 weeks on weekly semaglutide, against 2.4% for placebo, per NEJM, STEP 1.
Tirzepatide was approved for chronic weight management in November 2023, per FDA.
Neither platform's marketing changes any of that. It is the same evidence base whichever one takes your card.
Directmeds vs Refills: common questions
Which is cheaper to start, Directmeds or Refills?
Only Refills publishes a first-month figure (GLP-1 from $99/mo, about $5 a day). The other quotes after intake, so a starting-cost comparison is not available in advance.
How much does Directmeds cost?
Standard post-promotional pricing is not disclosed upfront. That is the honest answer, and it is the main practical drawback next to Refills, which publishes GLP-1 from $99/mo, about $5 a day upfront. If you go through the intake, ask for the month-two and maintenance-dose prices in writing before paying for the first month.
Which has more patient reviews, Directmeds or Refills?
Refills, with 7,400 against 3,400. Ratings across this market cluster tightly, so volume is the more useful signal: it indicates how much operational load the platform has already absorbed, not how good the medication is.
What happens if I stop taking the medication?
Both programs are month to month, which makes stopping easy and makes the consequence of stopping the thing to plan for: published extension data shows most of the lost weight returns within about a year. That is an argument for choosing on annual cost rather than entry price.
Are Directmeds and Refills legitimate?
Both are licensed telehealth platforms that route a prescription through a clinician review before anything is dispensed; neither sells medication without one. Directmeds operates on quoted only after intake with pricing quote only, after intake, Refills on flat rate at every dose, published upfront. The meaningful due diligence is on the medication category and the terms, not on whether the platforms are real.
The verdict
Neither of these two publishes enough for a clean cost verdict, which is itself the finding. Directmeds leads on a half-price first month and nationwide shipping with no insurance step; Refills leads on $99 flat at every dosage, from LegitScript-certified pharmacies with third-party USP testing.
Before choosing either, get the maintenance-dose price in writing. Without it, any comparison — including this one — is working with half the information.
Neither choice is irreversible. Start with the program whose weaknesses you can tolerate, and reassess at month three when you know how you respond to the medication.
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Disclaimers and methodology
Medical content is informational only and does not replace professional diagnosis, treatment, or emergency care.
Some links are affiliate links and may generate commission at no extra cost to you.
Pricing reflects what each provider published as of the sync date above and changes frequently; confirm the current rate, and the rate at your maintenance dose, before you pay. Six- and twelve-month totals are calculated from those published rates and exclude anything a provider bills separately.
eRxDoctor is an independent publisher. It is not a medical provider, is not affiliated with or endorsed by Directmeds or Refills, and does not sell treatment. Read our ranking methodology.